Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 16/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.34 |
| ▸ | CDC25B | P30305 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12856537 | 0.89 | PDK2 (0.49) | PDK2 | |
| SCHEMBL134303 | 0.89 | PDK2 (0.49) | PDK2 | |
| SCHEMBL14854149 | 0.83 | PDK2 (0.46) | PDK2 | |
| SCHEMBL132979 | 0.82 | PDK2 (0.50) | PDK2CYP2C8CYP2C9 | |
| SCHEMBL14252222 | 0.82 | PDK2 (0.43) | PDK2 | |
| SCHEMBL21397856 | 0.82 | PDK2 (0.42) | PDK2CDC25BCYP2C8CYP2C9 | |
| SCHEMBL14427826 | 0.82 | PDK2 (0.51) | PDK2 | |
| SCHEMBL15159214 | 0.82 | PDK2 (0.47) | PDK2 | |
| SCHEMBL13781081 | 0.81 | PDK2 (0.44) | PDK2 | |
| SCHEMBL18854160 | 0.81 | PDK2 (0.43) | PDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11535640-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2022-12-27 | — | — | US | disclosed |
| US-20200207794-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200207794-A1 | METAL COMPLEXES | IMMT, MCU, SOD1 | PDK2 2190/4885CDC25A 4341/4885CDC25B 4259/4885 |
| US-11535640-B2 | Metal complexes | IMMT, MCU, SOD1 | PDK2 2190/4885CDC25A 4341/4885CDC25B 4259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.