Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | RRM1 | P23921 | 8/20 | 0.39 |
| ▸ | RRM2 | P31350 | 8/20 | 0.39 |
| ▸ | RRM2B | Q7LG56 | 8/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | NAALAD2 | Q9Y3Q0 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731906 | 0.77 | CRAT (0.41) | ALDH1A1LMNAPOLBCA12CA1 | |
| SCHEMBL14269791 | 0.77 | LMNA (0.35) | ALDH1A1LMNAPOLBCA12CA1 | |
| SCHEMBL1144276 | 0.77 | CRAT (0.41) | ALDH1A1LMNAPOLBCA12CA1 | |
| SCHEMBL1144295 | 0.77 | CRAT (0.41) | ALDH1A1LMNAPOLBCA12CA1 | |
| SCHEMBL2821774 | 0.75 | CA12 (0.54) | ALDH1A1LMNAPOLBCA12CA1 | |
| SCHEMBL16151080 | 0.73 | ALDH1A1 (0.46) | ALDH1A1LMNAMEN1KMT2AEPHX1 | |
| SCHEMBL25978155 | 0.73 | MME (0.46) | ALDH1A1LMNAPOLBMMP1MMP2 | |
| SCHEMBL745482 | 0.72 | ALDH1A1 (0.54) | ALDH1A1LMNAMEN1KMT2AEPHX1 | |
| SCHEMBL17234339 | 0.72 | ITGB3 (0.38) | LMNAPOLBCA12CA1CA2 | |
| SCHEMBL17234584 | 0.72 | ITGB3 (0.38) | LMNAPOLBCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3078656-B1 | AMIDE DERIVATIVES OF N-UREA SUBSTITUTED AMINO ACIDS AS FORMYL PEPTIDE RECEPTOR LIKE-1 (FPRL-1) RECEPTOR MODULATORS | ALLERGAN INC (US) | 2020-07-01 | — | — | EP | disclosed |