Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 7/20 | 0.43 |
| ▸ | CA2 | P00918 | 7/20 | 0.43 |
| ▸ | CA12 | O43570 | 6/20 | 0.43 |
| ▸ | CA9 | Q16790 | 6/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | STK17B | O94768 | 1/20 | 0.37 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CCNC | P24863 | 1/20 | 0.34 |
| ▸ | CDK8 | P49336 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154752 | 0.92 | MAOA (0.47) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL1276827 | 0.86 | TDP1 (0.54) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL5136229 | 0.85 | SMN1; SMN2 (0.50) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL18747980 | 0.83 | MAOA (0.43) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL2459761 | 0.83 | MAOA (0.60) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL22175551 | 0.82 | TSHR (0.55) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL21738506 | 0.81 | SMN1; SMN2 (0.47) | MAOAMAOBTDP1MEN1GAA | |
| Bromide SCHEMBL25375155 | 0.81 | MAOA (0.65) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL22381487 | 0.80 | MAOA (0.64) | MAOAMAOBTDP1MEN1GAA | |
| SCHEMBL13471245 | 0.80 | SMN1; SMN2 (0.46) | MAOAMAOBTDP1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4257152-A2 | APELIN POLYPEPTIDES | Amgen Inc. (US) | 2023-10-11 | — | — | EP | disclosed |
| EP-3674314-A2 | APELIN POLYPEPTIDES | Amgen, Inc (US) | 2020-07-01 | — | — | EP | disclosed |