Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 3/20 | 0.39 |
| ▸ | CA2 | P00918 | 3/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22175642 | 0.92 | MAOA (0.55) | MAOAMAOBSMN1; SMN2TDP1GAA | |
| SCHEMBL5136229 | 0.88 | SMN1; SMN2 (0.50) | MAOAMAOBSMN1; SMN2TDP1GAA | |
| SCHEMBL1276792 | 0.85 | TDP1 (0.49) | MAOAMAOBSMN1; SMN2TDP1GAA | |
| SCHEMBL21738506 | 0.84 | SMN1; SMN2 (0.47) | MAOAMAOBSMN1; SMN2TDP1GAA | |
| SCHEMBL13471245 | 0.82 | SMN1; SMN2 (0.46) | MAOAMAOBSMN1; SMN2TDP1GAA | |
| SCHEMBL432412 | 0.82 | MAOA (0.51) | MAOAMAOBSMN1; SMN2TDP1GAA | |
| SCHEMBL7530750 | 0.81 | MAOA (0.57) | MAOAMAOBTDP1GAAMEN1 | |
| Hydrochloric Acid SCHEMBL5158594 | 0.81 | MAOA (0.50) | MAOAMAOBSMN1; SMN2TDP1GAA | |
| SCHEMBL18747980 | 0.81 | MAOA (0.43) | MAOAMAOBSMN1; SMN2TDP1GAA | |
| SCHEMBL1631203 | 0.80 | MAOA (0.44) | MAOAMAOBSMN1; SMN2TDP1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030207804-A1 | Modified peptide nucleic acids | ISIS PHARMACEUTICALS, INC. | 2003-11-06 | — | — | US | disclosed |
| WO-2002097134-A2 | MODIFIED PEPTIDE NUCLEIC ACID | ISIS PHARMACEUTICALS, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207804-A1 | Modified peptide nucleic acids | NGLY1, PARN, NPPA | MAOA 4491/4885MAOB 4231/4885SMN1; SMN2 1515/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.