Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | ADCY10 | Q96PN6 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22175912 | 0.72 | HPGD (0.53) | L3MBTL1KMT2AKDM4EHPGDALDH1A1 | |
| Hydrochloric Acid SCHEMBL22164322 | 0.72 | HPGD (0.52) | L3MBTL1KMT2AKDM4EHPGDALDH1A1 | |
| SCHEMBL22749175 | 0.71 | CNR2 (0.47) | CNR2L3MBTL1KMT2AKDM4EGLA | |
| SCHEMBL21960946 | 0.71 | CNR2 (0.55) | CNR2L3MBTL1KMT2AKDM4EGLA | |
| SCHEMBL22749221 | 0.70 | CNR2 (0.46) | CNR2L3MBTL1KMT2AKDM4EGLA | |
| SCHEMBL25796607 | 0.70 | CNR2 (0.53) | CNR2L3MBTL1KMT2AKDM4EGLA | |
| SCHEMBL22749219 | 0.69 | CNR2 (0.45) | CNR2L3MBTL1KMT2AKDM4EGLA | |
| SCHEMBL22175884 | 0.69 | ALDH1A1 (0.43) | L3MBTL1KDM4EHPGDALDH1A1MAPT | |
| SCHEMBL19893122 | 0.69 | CNR2 (0.47) | CNR2L3MBTL1KMT2AKDM4EGLA | |
| SCHEMBL22164260 | 0.68 | METAP2 (0.45) | KDM4EGAAHPGDALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138015-A1 | PYRAZOLO[1,5-A]PYRIMIDINE MACROCYCLIC COMPOUND | 大正製薬株式会社 | 2020-07-02 | — | — | WO | disclosed |