Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HCAR3 | P49019 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | KDM6B | O15054 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22749175 | 0.96 | CNR2 (0.47) | CNR2KDM4EGAAHCAR3KMT2A | |
| SCHEMBL22749219 | 0.88 | CNR2 (0.45) | CNR2KDM4EGAAKMT2AMEN1 | |
| SCHEMBL22749220 | 0.76 | ALDH1A1 (0.36) | CNR2KDM4EGAAKMT2AMEN1 | |
| SCHEMBL21960946 | 0.76 | CNR2 (0.55) | CNR2KDM4EGAAKMT2AMEN1 | |
| SCHEMBL25796607 | 0.74 | CNR2 (0.53) | CNR2KDM4EGAAKMT2AMEN1 | |
| SCHEMBL22749207 | 0.73 | CNR2 (0.47) | CNR2KDM4EGAAHCAR3MGLL | |
| SCHEMBL21000857 | 0.72 | SMN1; SMN2 (0.50) | CNR2KDM4EGAAKMT2AMEN1 | |
| SCHEMBL4443917 | 0.72 | CNR2 (0.47) | CNR2KDM4EGAAKMT2AMEN1 | |
| SCHEMBL17923514 | 0.72 | CNR2 (0.51) | CNR2KDM4EGAAKMT2AMEN1 | |
| SCHEMBL22175937 | 0.70 | CNR2 (0.42) | CNR2KDM4EGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12358919-B2 | Antibacterial compounds | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2025-07-15 | — | — | US | disclosed |
| US-20220235059-A1 | ANTIBACTERIAL COMPOUNDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2022-07-28 | — | — | US | disclosed |
| EP-3980418-A1 | ANTIBACTERIAL COMPOUNDS | Universita' Degli Studi di Siena (IT) | 2022-04-13 | — | — | EP | disclosed |
| WO-2020245759-A1 | ANTIBACTERIAL COMPOUNDS | UNIVERSITA' DEGLI STUDI DI SIENA (IT) | 2020-12-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12358919-B2 | Antibacterial compounds | ABCB11, CFTR, MRPL21 | CNR2 4529/4885KDM4E 3651/4885GAA 49/4885 |
| US-20220235059-A1 | ANTIBACTERIAL COMPOUNDS | ABCB11, CFTR, MRPL21 | CNR2 4529/4885KDM4E 3651/4885GAA 49/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.