Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.39 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30311378 | 1.00 | KLK7 (0.41) | KLK7PRMT5AADATTSHRNPSR1 | |
| SCHEMBL30311334 | 0.88 | KLK7 (0.40) | KLK7PRMT5AADATTSHRNPSR1 | |
| SCHEMBL22164278 | 0.86 | TSHR (0.34) | TSHRNPSR1MAPTLMNAALDH1A1 | |
| SCHEMBL22175845 | 0.86 | TSHR (0.34) | TSHRNPSR1MAPTLMNAALDH1A1 | |
| SCHEMBL2737942 | 0.84 | PDE8B (0.40) | TSHRNPSR1MAPTLMNAALDH1A1 | |
| SCHEMBL22175827 | 0.83 | PDE8B (0.37) | TSHRNPSR1MAPTLMNAALDH1A1 | |
| SCHEMBL22164263 | 0.83 | PDE8B (0.37) | TSHRNPSR1MAPTLMNAALDH1A1 | |
| SCHEMBL30311180 | 0.81 | KLK7 (0.41) | KLK7PRMT5AADATTSHRNPSR1 | |
| SCHEMBL22164195 | 0.79 | TSHR (0.40) | TSHRNPSR1MAPTLMNAALDH1A1 | |
| SCHEMBL30311213 | 0.79 | AADAT (0.38) | KLK7PRMT5AADATTSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020138015-A1 | PYRAZOLO[1,5-A]PYRIMIDINE MACROCYCLIC COMPOUND | 大正製薬株式会社 | 2020-07-02 | — | — | WO | disclosed |