Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.76 |
| ▸ | MAP3K11 | Q16584 | 2/20 | 0.56 |
| ▸ | GUSB | P08236 | 3/20 | 0.52 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.51 |
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.47 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.47 |
| ▸ | ITGAL | P20701 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | ADK | P55263 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL446619 | 0.86 | NPC1 (1.00) | NPC1MAP3K11GUSBGLO1AHR | |
| SCHEMBL30587350 | 0.86 | NPC1 (1.00) | NPC1MAP3K11GUSBGLO1AHR | |
| SCHEMBL28210414 | 0.85 | NPC1 (0.96) | NPC1MAP3K11GUSBGLO1AHR | |
| SCHEMBL16918805 | 0.84 | NPC1 (0.62) | NPC1MAP3K11GUSBGLO1AHR | |
| SCHEMBL20120884 | 0.83 | NPC1 (0.92) | NPC1MAP3K11GLO1AHRCA1 | |
| Indole SCHEMBL29263536 | 0.82 | TRPA1 (0.71) | NPC1MAP3K11GUSBGLO1AHR | |
| SCHEMBL22178774 | 0.82 | NPC1 (0.61) | NPC1MAP3K11GUSBMETAHR | |
| SCHEMBL31504070 | 0.82 | NPC1 (0.61) | NPC1MAP3K11GUSBMETAHR | |
| SCHEMBL398355 | 0.82 | NPC1 (0.61) | NPC1MAP3K11GUSBAHRCA1 | |
| SCHEMBL27500073 | 0.82 | GUSB (0.68) | NPC1MAP3K11GUSBGLO1CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200212315-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND | IDEMITSU KOSAN CO.,LTD. (JP) | 2020-07-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200212315-A1 | ORGANIC ELECTROLUMINESCENT ELEMENT, ELECTRONIC DEVICE, AND COMPOUND | OR10J3, ESR1, NFE2L2 | NPC1 3282/4885MAP3K11 2430/4885GUSB 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.