SCHEMBL22181543

SCHEMBL22181543

c1ccc(-c2c3ccccc3c(-c3ccccc3-c3ccc4c(c3)B3c5ccccc5Oc5cccc(c53)O4)c3ccc4ccccc4c23)cc1

nearest known ligand 0.32

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CYP1A1 P04798 1/20 0.31
CYP1A2 P05177 1/20 0.31
FYN P06241 1/20 0.31
MAPK3 P27361 1/20 0.31
AHR P35869 1/20 0.31
PAX8 Q06710 1/20 0.31
ABCG2 Q9UNQ0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22181542 0.94 KDM4E (0.32) KDM4EMEN1KMT2ACYP1A1CYP1A2
SCHEMBL23432483 0.92 ABCG2 (0.33) KDM4EMEN1KMT2ACYP1A1CYP1A2
SCHEMBL22181541 0.90 KDM4E (0.34) KDM4EMEN1KMT2ACYP1A1CYP1A2
SCHEMBL22159676 0.88 GPR84 (0.32)
SCHEMBL22181303 0.87 GPR84 (0.32)
SCHEMBL22181274 0.87 MCL1 (0.32) KDM4ECYP1A2
SCHEMBL22181366 0.87 GPR84 (0.35)
SCHEMBL22181535 0.87 KDM4E (0.32) KDM4EMEN1KMT2AABCG2
SCHEMBL22181728 0.87 SOS1 (0.40)
SCHEMBL22181315 0.86 GPR84 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11248009-B2 Polycyclic aromatic compound, material for an organic device, organic electroluminescent element, display apparatus and lighting apparatus KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2022-02-15 US disclosed
US-20200207787-A1 POLYCYCLIC AROMATIC COMPOUND, MATERIAL FOR AN ORGANIC DEVICE, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY APPARATUS AND LIGHTING APPARATUS KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2020-07-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11248009-B2 Polycyclic aromatic compound, material for an organic device, organic electroluminescent element, display apparatus and lighting apparatus TYR, AOC2, AOC1 KDM4E 2025/4885MEN1 2682/4885KMT2A 1636/4885
US-20200207787-A1 POLYCYCLIC AROMATIC COMPOUND, MATERIAL FOR AN ORGANIC DEVICE, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY APPARATUS AND LIGHTING APPARATUS TYR, AOC2, AOC1 KDM4E 2025/4885MEN1 2682/4885KMT2A 1636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.