Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PARP1 | P09874 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.33 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | HEXA | P06865 | 1/20 | 0.31 |
| ▸ | HEXB | P07686 | 1/20 | 0.31 |
| ▸ | AXL | P30530 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22181900 | 0.82 | MEN1 (0.39) | MEN1KMT2APOLBCASP1ALDH1A1 | |
| SCHEMBL22181928 | 0.80 | SIRT1 (0.49) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL22182009 | 0.79 | MEN1 (0.34) | MEN1KMT2APOLBCASP1ALDH1A1 | |
| SCHEMBL22182063 | 0.75 | DNMT1 (0.38) | MEN1KMT2APOLBCASP1ALDH1A1 | |
| SCHEMBL22182103 | 0.74 | DNMT1 (0.40) | MEN1KMT2APOLBCASP1ALDH1A1 | |
| SCHEMBL22181867 | 0.73 | HEXA (0.47) | MEN1KMT2APOLBCASP1ALDH1A1 | |
| SCHEMBL22181932 | 0.69 | MEN1 (0.43) | MEN1KMT2APOLBCASP1ALDH1A1 | |
| SCHEMBL24418023 | 0.65 | SIRT1 (0.47) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL22181861 | 0.64 | SIRT1 (0.53) | MEN1KMT2APOLBALDH1A1MAPT | |
| SCHEMBL22181976 | 0.64 | NPC1 (0.54) | PIP4K2APIP4K2BNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020139291-A1 | NAPHTHALIMIDE DERIVATIVES AS ANTI-PARASITIC AGENTS FOR THE TREATMENT OF LEISHMANIASIS AS WELL AS VIRAL, BACTERIAL AND NEOPLASTIC DISEASES | ISTANBUL MEDIPOL UNIVERSITESI (TR) | 2020-07-02 | — | — | WO | disclosed |