Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RGS12 | O14924 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HEXA | P06865 | 1/20 | 0.35 |
| ▸ | HEXB | P07686 | 1/20 | 0.35 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22181933 | 0.81 | SIRT1 (0.54) | MEN1KMT2APOLBCASP1MAPT | |
| SCHEMBL22181867 | 0.80 | HEXA (0.47) | MEN1KMT2APOLBCASP1MAPT | |
| SCHEMBL22182103 | 0.71 | DNMT1 (0.40) | MEN1KMT2APOLBCASP1MAPT | |
| SCHEMBL22181927 | 0.69 | MEN1 (0.38) | MEN1KMT2APOLBCASP1MAPT | |
| SCHEMBL22182063 | 0.69 | DNMT1 (0.38) | MEN1KMT2APOLBCASP1MAPT | |
| SCHEMBL22181900 | 0.69 | MEN1 (0.39) | MEN1KMT2APOLBCASP1MAPT | |
| SCHEMBL22181920 | 0.68 | SIRT1 (0.61) | MEN1KMT2APOLBCASP1MAPT | |
| SCHEMBL11076680 | 0.67 | CNR1 (0.49) | MEN1KMT2APOLBMAPTHTT | |
| SCHEMBL22181840 | 0.65 | SIRT1 (0.57) | MEN1KMT2APOLBMAPTHTT | |
| SCHEMBL1672292 | 0.64 | MEN1 (0.58) | MEN1KMT2APOLBCASP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020139291-A1 | NAPHTHALIMIDE DERIVATIVES AS ANTI-PARASITIC AGENTS FOR THE TREATMENT OF LEISHMANIASIS AS WELL AS VIRAL, BACTERIAL AND NEOPLASTIC DISEASES | ISTANBUL MEDIPOL UNIVERSITESI (TR) | 2020-07-02 | — | — | WO | disclosed |