Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | UBE2N | P61088 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | MPI | P34949 | 1/20 | 0.44 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.44 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HEXA | P06865 | 3/20 | 0.43 |
| ▸ | HEXB | P07686 | 3/20 | 0.43 |
| ▸ | HTR7 | P34969 | 6/20 | 0.43 |
| ▸ | HTR1A | P08908 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 5/20 | 0.43 |
| ▸ | HTR2A | P28223 | 5/20 | 0.43 |
| ▸ | HTR6 | P50406 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22181936 | 0.92 | SIRT1 (0.54) | SIRT1HPGDALDH1A1SMN1; SMN2HEXA | |
| SCHEMBL22181934 | 0.78 | SIRT1 (0.55) | SIRT1HPGDALDH1A1HEXAHEXB | |
| SCHEMBL22181984 | 0.77 | POLB (0.43) | SIRT1HPGDUBE2NALDH1A1CASP1 | |
| SCHEMBL22181924 | 0.77 | SIRT1 (0.54) | SIRT1HPGDALDH1A1HEXAHEXB | |
| SCHEMBL9720971 | 0.74 | HPGD (0.70) | HPGDUBE2NLMNAATML3MBTL1 | |
| SCHEMBL22181921 | 0.74 | SIRT1 (0.56) | SIRT1ATML3MBTL1ALDH1A1CASP1 | |
| SCHEMBL29632727 | 0.74 | SIRT1 (0.56) | SIRT1ATML3MBTL1ALDH1A1CASP1 | |
| SCHEMBL22181861 | 0.74 | SIRT1 (0.53) | SIRT1HPGDALDH1A1HEXAHEXB | |
| SCHEMBL22181854 | 0.73 | SIRT1 (0.57) | SIRT1HPGDALDH1A1SMN1; SMN2HEXA | |
| SCHEMBL22181918 | 0.72 | SIRT1 (0.60) | SIRT1HPGDATML3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020139291-A1 | NAPHTHALIMIDE DERIVATIVES AS ANTI-PARASITIC AGENTS FOR THE TREATMENT OF LEISHMANIASIS AS WELL AS VIRAL, BACTERIAL AND NEOPLASTIC DISEASES | ISTANBUL MEDIPOL UNIVERSITESI (TR) | 2020-07-02 | — | — | WO | disclosed |