Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1F | O60840 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14176514 | 0.85 | CACNA1F (0.39) | CACNA1FCHRM2CHRM1ADRA2BCHRM3 | |
| SCHEMBL15171895 | 0.79 | ADH1B (0.47) | CACNA1FCHRM2CHRM1ADRA2BCHRM3 | |
| SCHEMBL20707027 | 0.79 | LMNA (0.40) | CACNA1FCHRM2CHRM1ADRA2BCHRM3 | |
| SCHEMBL24311659 | 0.77 | CACNA1F (0.34) | CACNA1FCHRM2CHRM1ADRA2BCHRM3 | |
| SCHEMBL10706764 | 0.76 | CA2 (0.39) | CACNA1FCHRM2CHRM1ADRA2BCHRM3 | |
| SCHEMBL12617185 | 0.76 | LMNA (0.42) | CACNA1FCHRM2CHRM1ADRA2BCHRM3 | |
| SCHEMBL24191897 | 0.74 | CACNA1F (0.35) | CACNA1FCHRM2CHRM1ADRA2BCHRM3 | |
| SCHEMBL24191896 | 0.74 | CACNA1F (0.35) | CACNA1FCHRM2CHRM1ADRA2BCHRM3 | |
| SCHEMBL24191892 | 0.74 | CACNA1F (0.35) | CACNA1FCHRM2CHRM1ADRA2BCHRM3 | |
| SCHEMBL18997681 | 0.74 | CACNA1F (0.35) | CACNA1FCHRM2CHRM1ADRA2BCHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3674300-A1 | NOVEL BICYCLIC BROMODOMAIN INHIBITORS | Zenith Epigenetics Ltd. (CA) | 2020-07-01 | — | — | EP | disclosed |