Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.73 |
| ▸ | RAB9A | P51151 | 4/20 | 0.73 |
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.59 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.59 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.59 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.59 |
| ▸ | EPHX1 | P07099 | 7/20 | 0.58 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17727554 | 0.87 | — | — | |
| SCHEMBL4191605 | 0.86 | NPC1 (0.73) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL23736058 | 0.85 | NPC1 (1.00) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL3076504 | 0.85 | NPC1 (1.00) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL8165938 | 0.85 | NPC1 (1.00) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL2377367 | 0.85 | NPC1 (1.00) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL14877484 | 0.83 | SMN1; SMN2 (0.68) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL585161 | 0.82 | NPC1 (0.67) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL6431914 | 0.82 | NPC1 (0.67) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 | |
| SCHEMBL23506579 | 0.82 | NPC1 (0.67) | NPC1SMN1; SMN2RAB9AMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9340498-B2 | Raft polymerisation | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESERACH ORGANISATION (AU) | 2016-05-17 | — | — | US | claimed |
| WO-2023102600-A1 | SYNTHESIS OF AMPHIPHILIC BLOCK COPOLYMERS AND POLYMERIC NANOFIBERS PRODUCED THEREFROM | NEWSOUTH INNOVATIONS PTY LIMITED (AU) | 2023-06-15 | — | — | WO | disclosed |
| EP-2389395-B1 | RAFT POLYMERISATION | COMMW SCIENT IND RES ORG (AU) | 2017-03-29 | — | — | EP | disclosed |
| US-9340498-B2 | Raft polymerisation | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESERACH ORGANISATION (AU) | 2016-05-17 | — | — | US | disclosed |
| US-20120004381-A1 | RAFT POLYMERISATION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2012-01-05 | — | — | US | disclosed |
| EP-2389395-A1 | RAFT POLYMERISATION | Commonwealth Scientific and Industrial Research Organisation (AU) | 2011-11-30 | — | — | EP | disclosed |
| US-20110256644-A1 | MASKS FOR MICROLITHOGRAPHY AND METHODS OF MAKING AND USING SUCH MASKS | MICRON TECHNOLOGY, INC. (US) | 2011-10-20 | — | — | US | disclosed |
| WO-2010083569-A1 | RAFT POLYMERISATION | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2010-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120004381-A1 | RAFT POLYMERISATION | OXGR1, FRG1, MSR1 | NPC1 340/4885SMN1; SMN2 1215/4885RAB9A 3808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.