SCHEMBL2218540

SCHEMBL2218540

CCCCCCCC/C=C\CCCCCCCCOC(CO)CO

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 3/20 0.87
CNR2 P34972 3/20 0.87
ALDH1A1 P00352 2/20 0.87
LPAR1 Q92633 1/20 0.50
LPAR2 Q9HBW0 1/20 0.50
LPAR3 Q9UBY5 1/20 0.50
PRKCE Q02156 1/20 0.50
PRKCQ Q04759 1/20 0.50
PRKCD Q05655 1/20 0.50
PRKCA P17252 1/20 0.50
FAAH O00519 1/20 0.50
MAPT P10636 1/20 0.50
HPGD P15428 1/20 0.50
DNM1 Q05193 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2218546 1.00 CNR1 (0.87) CNR1CNR2ALDH1A1LPAR1LPAR2
Water SCHEMBL11118961 0.98 CNR1 (0.84) CNR1CNR2ALDH1A1LPAR1LPAR2
SCHEMBL12023406 0.95 CNR1 (0.97) CNR1CNR2ALDH1A1FAAHMAPT
SCHEMBL4645046 0.95 CNR1 (0.97) CNR1CNR2ALDH1A1FAAHMAPT
SCHEMBL495999 0.93 CNR1 (1.00) CNR1CNR2ALDH1A1FAAHMAPT
SCHEMBL496000 0.93 CNR1 (1.00) CNR1CNR2ALDH1A1FAAHMAPT
SCHEMBL3690975 0.93 CNR1 (1.00) CNR1CNR2ALDH1A1FAAHMAPT
SCHEMBL632823 0.91 CNR1 (0.73) CNR1CNR2ALDH1A1LPAR1LPAR3
SCHEMBL24208055 0.90 CNR1 (0.71) CNR1CNR2ALDH1A1LPAR1LPAR2
SCHEMBL10492075 0.90 CNR1 (0.71) CNR1CNR2ALDH1A1LPAR1LPAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-5023135-A None JP disclosed
US-20250288622-A1 USE OF AKKERMANSIA FOR TREATING METABOLIC DISORDERS WAGENINGEN UNIVERSITEIT (NL) 2025-09-18 US disclosed
US-20250288621-A1 USE OF AKKERMANSIA FOR TREATING METABOLIC DISORDERS COMPAGNIE GERVAIS DANONE (FR) 2025-09-18 US disclosed
US-12371401-B2 Dithienyl disulfiram derivatives as selective ALDH1A1 inhibitors BATTERJEE MEDICAL COLLEGE (SA) 2025-07-29 US disclosed
EP-3967315-B1 AKKERMANSIA MUCINIPHILA FOR TREATING CANCER UNIV CATHOLIQUE LOUVAIN (BE) 2025-05-14 EP disclosed
US-20250145565-A1 DITHIENYL DISULFIRAM DERIVATIVES AS SELECTIVE ALDH1A1 INHIBITORS BATTERJEE MEDICAL COLLEGE (SA) 2025-05-08 US disclosed
EP-3862010-B1 USE OF AKKERMANSIA MUCINIPHILA FOR PROMOTING WEIGHT LOSS UNIV CATHOLIQUE LOUVAIN (BE) 2025-05-07 EP disclosed
EP-4512479-A2 UTILISATION D'AKKERMANSIA POUR LE TRAITEMENT DE TROUBLES MÉTABOLIQUES Université Catholique de Louvain (BE) 2025-02-26 EP disclosed
EP-4509182-A2 UTILISATION D'AKKERMANSIA POUR LE TRAITEMENT DE TROUBLES MÉTABOLIQUES Université Catholique de Louvain (BE) 2025-02-19 EP disclosed
EP-4509181-A2 UTILISATION D'AKKERMANSIA POUR LE TRAITEMENT DE TROUBLES MÉTABOLIQUES Université Catholique de Louvain (BE) 2025-02-19 EP disclosed
EP-1291376-B1 SILICONE POLYMER, SILICONE COMPOSITION, AND COSMETIC PREPARATION CONTAINING THE SAME SHINETSU CHEMICAL CO (JP) 2009-12-09 EP disclosed
WO-2009064696-A1 STEROL-MODIFIED AMPHIPHILIC LIPIDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2009-05-22 WO disclosed
CN-101410128-A Use of probiotic micro-organisms for the treatment and prevention of obesity and related disorders DANISCO (DK) 2009-04-15 CN disclosed
EP-1981516-A2 USE OF PROBIOTIC MICROORGANISMS FOR THE TREATMENT AND PREVENTION OF OBESITY AND RELATED DISORDERS Danisco A/S (DK) 2008-10-22 EP disclosed
WO-2007085970-A2 USE OF PROBIOTIC MICROORGANISMS FOR THE TREATMENT AND PREVENTION OF OBESITY AND RELATED DISORDERS DANISCO A/S (DK) 2007-08-02 WO disclosed
EP-1291376-A1 SILICONE POLYMER, SILICONE COMPOSITION, AND COSMETIC PREPARATION CONTAINING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-03-12 EP disclosed
US-5607970-A GLYCEROL MONOSTEARATE OR PALMITATE KABUSHIKI KAISYA ADVANCE (JP) 1997-03-04 US disclosed
WO-1996023811-A1 SITOSTEROL- AND ACYLGLYCEROL-BASED ORGANOMETALLIC COMPLEXES, AND PHARMACEUTICAL COMPOSITIONS AND DIET PRODUCTS CONTAINING SAME MAUREL SANTE (FR) 1996-08-08 WO disclosed
EP-0549804-A1 ACAT INHIBITOR KABUSHIKI KAISYA ADVANCE (JP) 1993-07-07 EP disclosed
JP-H0523135-A ACAT INHIBITOR ADVANCE CO LTD 1993-02-02 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12371401-B2 Dithienyl disulfiram derivatives as selective ALDH1A1 inhibitors ALDH3A1, ALDH1A1, ADH1A CNR1 3432/4885CNR2 3303/4885ALDH1A1 2/4885
US-20250145565-A1 DITHIENYL DISULFIRAM DERIVATIVES AS SELECTIVE ALDH1A1 INHIBITORS ALDH3A1, ALDH1A1, ADH1A CNR1 3432/4885CNR2 3303/4885ALDH1A1 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.