Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 10/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | FPR2 | P25090 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | SMURF1 | Q9HCE7 | 1/20 | 0.38 |
| ▸ | LPL | P06858 | 1/20 | 0.38 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28605634 | 1.00 | FFAR4 (0.44) | FFAR4DRD3NOTUMFPR2SCN9A | |
| SCHEMBL28918772 | 0.85 | FFAR4 (0.42) | FFAR4DRD3SMURF1LPLLIPG | |
| SCHEMBL28601654 | 0.84 | LMNA (0.46) | LPLLIPG | |
| SCHEMBL28601649 | 0.84 | LMNA (0.46) | LPLLIPG | |
| SCHEMBL22186372 | 0.80 | PIM1 (0.47) | FFAR4DRD3NOTUM | |
| Hydrochloric Acid SCHEMBL28596260 | 0.79 | PIM1 (0.46) | FFAR4DRD3 | |
| Hydrochloric Acid SCHEMBL28596259 | 0.79 | PIM1 (0.46) | FFAR4DRD3 | |
| SCHEMBL28601507 | 0.77 | LIPG (0.52) | LPLLIPG | |
| SCHEMBL28601509 | 0.77 | LIPG (0.52) | LPLLIPG | |
| SCHEMBL28918773 | 0.74 | BTK (0.49) | FFAR4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164461-A | Heterocyclic derivatives as Nav1.7 and Nav1.8 blockers | 拉夸里亚创药株式会社 | 2021-07-23 | — | — | CN | disclosed |