Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 1/20 | 0.50 |
| ▸ | MARS1 | P56192 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22186993 | 0.81 | MARS1 (0.58) | MARS1KDM4E | |
| SCHEMBL22186989 | 0.76 | MITF (0.46) | CNR1CNR2KDM4ELMNAEGFR | |
| SCHEMBL9584734 | 0.74 | FFAR1 (0.49) | CNR2KDM4EAPPLMNARXFP1 | |
| Hydrochloric Acid SCHEMBL9583857 | 0.73 | FFAR1 (0.48) | CNR2KDM4EAPPLMNARXFP1 | |
| SCHEMBL5670545 | 0.73 | MARS1 (0.57) | MARS1 | |
| SCHEMBL21667281 | 0.72 | EGFR (0.53) | CNR1CNR2KDM4ETDO2RXFP1 | |
| SCHEMBL5669209 | 0.72 | MARS1 (0.64) | MARS1 | |
| SCHEMBL6521513 | 0.71 | AURKA (0.56) | CNR1CNR2APPTDO2RXFP1 | |
| SCHEMBL5668780 | 0.71 | MARS1 (0.77) | MARS1 | |
| SCHEMBL5669849 | 0.71 | MARS1 (0.76) | MARS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020136693-A1 | SUBSTITUTED QUINOLONE COMPOUNDS, THEIR USE IN THE TREATMENT OF CANCER, AND A METHOD FOR PREPARATION | UNIVERSITY OF PETRA (JO) | 2020-07-02 | — | — | WO | disclosed |