Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | OXTR | P30559 | 5/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | AVPR1B | P47901 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20772747 | 0.84 | SMN1; SMN2 (0.49) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL20773830 | 0.84 | KMT2A (0.48) | ALDH1A1MEN1KMT2ATSHRMAPT | |
| SCHEMBL20773155 | 0.84 | POLB (0.48) | ALDH1A1ALOX15MEN1KMT2ATSHR | |
| SCHEMBL20773041 | 0.81 | GAA (0.48) | ALDH1A1KDM4EHSD17B10ALOX15MEN1 | |
| SCHEMBL22109033 | 0.81 | KMT2A (0.46) | ALDH1A1KDM4EALOX15MEN1KMT2A | |
| SCHEMBL29779980 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4EMEN1KMT2ATSHR | |
| SCHEMBL20773176 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KDM4EMEN1KMT2ATSHR | |
| SCHEMBL20777381 | 0.80 | MGLL (0.44) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL20772764 | 0.80 | TRPM8 (0.42) | ALDH1A1KDM4EHSD17B10ALOX15MEN1 | |
| SCHEMBL29779983 | 0.80 | TRPM8 (0.42) | ALDH1A1KDM4EHSD17B10ALOX15MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3675809-A1 | USE OF PHYSIOLOGICAL COOLING ACTIVE INGREDIENTS, AND COMPOSITIONS COMPRISING SUCH ACTIVE INGREDIENTS | BASF SE (DE) | 2020-07-08 | — | — | EP | disclosed |