SCHEMBL22188162

SCHEMBL22188162

OB(O)c1cc(C23CC4CC(CC(C4)C2)C3)cc(C23CC4CC(CC(C4)C2)C3)c1

nearest known ligand 0.47

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
GAA P10253 2/20 0.47
POLB P06746 1/20 0.47
GFER P55789 1/20 0.47
LMNA P02545 3/20 0.42
ALDH1A1 P00352 2/20 0.42
HIF1A Q16665 1/20 0.40
EPHX2 P34913 4/20 0.40
NPC1 O15118 1/20 0.38
MAPT P10636 2/20 0.36
USP2 O75604 1/20 0.35
THRB P10828 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
RAB9A P51151 1/20 0.35
CNR2 P34972 6/20 0.33
CNR1 P21554 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28932564 0.82 MEN1 (0.50) MEN1KMT2AGAAPOLBGFER
SCHEMBL31005165 0.82 MEN1 (0.50) MEN1KMT2AGAAPOLBGFER
SCHEMBL25709750 0.80 LMNA (0.57) MEN1KMT2AGAAPOLBGFER
SCHEMBL2709431 0.80 LMNA (0.57) MEN1KMT2AGAAPOLBGFER
SCHEMBL548788 0.77 MEN1 (0.57) MEN1KMT2AGAAPOLBGFER
SCHEMBL24522091 0.72 ALDH1A1 (0.63) MEN1KMT2AGAAPOLBGFER
SCHEMBL11642014 0.72 MEN1 (0.57) MEN1KMT2AGAAPOLBGFER
SCHEMBL17358864 0.71 MEN1 (0.46) MEN1KMT2AGAAPOLBGFER
SCHEMBL7906252 0.71 RARB (0.49) MEN1KMT2AGAAPOLBGFER
SCHEMBL27847928 0.70 MEN1 (0.59) MEN1KMT2AGAAPOLBGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12577268-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2026-03-17 US disclosed
CN-117304234-A Organic electroluminescent material and device 环球展览公司 2023-12-29 CN disclosed
US-11814403-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-11-14 US disclosed
CN-111747989-B Organic electroluminescent material and device 环球展览公司 2023-10-31 CN disclosed
EP-4134371-A2 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2023-02-15 EP disclosed
EP-3715353-B1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORP (US) 2022-09-14 EP disclosed
US-20210284672-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-09-16 US disclosed
WO-2021036683-A1 AROMATIC AMINE COMPOUND, COATING LAYER MATERIAL AND LIGHT EMITTING ELEMENT 东丽先端材料研究开发(中国)有限公司 2021-03-04 WO disclosed
CN-111747989-A Organic electroluminescent material and device 环球展览公司 2020-10-09 CN disclosed
EP-3715353-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Universal Display Corporation (US) 2020-09-30 EP disclosed
US-20200216481-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210284672-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDCD1, TEC, PDCD4 MEN1 452/4885KMT2A 1732/4885GAA 4316/4885
US-11814403-B2 Organic electroluminescent materials and devices PDCD1, TEC, PDCD4 MEN1 495/4885KMT2A 1758/4885GAA 4318/4885
US-12577268-B2 Organic electroluminescent materials and devices LBR, RPS4X, RPS6 MEN1 2786/4885KMT2A 2216/4885GAA 4651/4885
US-20200216481-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES PDCD1, TEC, PDCD4 MEN1 495/4885KMT2A 1758/4885GAA 4318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.