SCHEMBL2218862

SCHEMBL2218862

ClB(c1ccccc1)c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ORAI1 Q96D31 3/20 0.53
ORAI2 Q96SN7 3/20 0.53
ORAI3 Q9BRQ5 3/20 0.53
TRPV6 Q9H1D0 3/20 0.53
CA4 P22748 2/20 0.47
CA6 P23280 1/20 0.47
CA5A P35218 1/20 0.47
CA7 P43166 1/20 0.47
ENPP2 Q13822 1/20 0.47
CA14 Q9ULX7 1/20 0.47
CA5B Q9Y2D0 1/20 0.47
PCSK9 Q8NBP7 1/20 0.47
BBOX1 O75936 4/20 0.40
EHMT2 Q96KQ7 3/20 0.40
EHMT1 Q9H9B1 3/20 0.40
TSHR P16473 5/20 0.39
ALDH1A1 P00352 3/20 0.36
TDP1 Q9NUW8 2/20 0.36
HSD17B10 Q99714 1/20 0.36
MGLL Q99685 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29194250 0.97 ORAI1 (0.50) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL8966944 0.86 ORAI1 (0.42) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL17352041 0.82 MGLL (0.56) ORAI1ORAI2ORAI3TRPV6ALDH1A1
SCHEMBL29602 0.79
SCHEMBL29260691 0.76
SCHEMBL17796990 0.76
SCHEMBL14829621 0.73
SCHEMBL125450 0.69 TRPV6 (0.53) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL435243 0.69 TRPV6 (1.00) ORAI1ORAI2ORAI3TRPV6CA4
SCHEMBL8966998 0.67 ORAI1 (0.42) ORAI1ORAI2ORAI3TRPV6CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 178 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080408-A Carbon dioxide-based sulfur-containing terpolymer and preparation method thereof 2026-05-26 CN claimed
CN-116497346-A Reduction solution for ionic palladium and preparation method and application thereof 深圳市富利特科技有限公司 2023-07-28 CN claimed
CN-113096858-B Wear-resistant and compression-resistant cable for drag chain and preparation method thereof 扬州鸿睿电缆科技有限公司 2023-03-17 CN claimed
CN-113594461-B Carbon-silicon composite material and preparation method and application thereof 常州烯源谷新材料科技有限公司 2022-05-31 CN claimed
CN-113594461-A Carbon-silicon composite material and preparation method and application thereof 常州烯源谷新材料科技有限公司 2021-11-02 CN claimed
CN-113096865-A High-strength wear-resistant cable for vertical pulling movement and preparation method thereof 扬州鸿睿电缆科技有限公司 2021-07-09 CN claimed
CN-113096858-A Wear-resistant and compression-resistant cable for drag chain and preparation method thereof 扬州鸿睿电缆科技有限公司 2021-07-09 CN claimed
CN-112174991-A Fluorescent dye excited and emitted by second window in near infrared region, and preparation method and application thereof 复旦大学 2021-01-05 CN claimed
CN-107936600-B Insulated cable and preparation method thereof 浙江南大电缆有限公司 2020-06-09 CN claimed
CN-108748533-A A kind of timber boracic preservative 阜南县永兴工艺品有限公司 2018-11-06 CN claimed
CN-107936600-A Insulated cable and preparation method thereof 浙江南大电缆有限公司 2018-04-20 CN claimed
CN-106350834-A Novel additive for electrolytic manganese electrolysis and preparation method thereof 中信大锰矿业有限责任公司 2017-01-25 CN claimed
US-5118829-A Organoborane compound catalyst DOW CORNING CORPORATION (US) 1992-06-02 US claimed
CN-122080408-A Carbon dioxide-based sulfur-containing terpolymer and preparation method thereof 2026-05-26 CN disclosed
US-20260139129-A1 Polyethylene Resin Composition SONG, Christine Jisoo (KR) 2026-05-21 US disclosed
CN-122025270-A High-flame-retardance temperature-resistant modified polyolefin low-voltage cable and preparation method thereof 河北英泰电气线缆有限公司 2026-05-12 CN disclosed
EP-0058549-A2 Catalyst for polymerization of olefins Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-08-25 EP disclosed
US-4279976-A COMPLEX ANION SALT IN AN ORGANIC SOLVENTS PROVIDES HIGH CONDUCTIVITY EXXON RESEARCH & ENGINEERING CO. (US) 1981-07-21 US disclosed
US-4121032-A Process for preparing alternating copolymer of conjugated vinyl compound and olefinic unsaturated compound with oxygen and boron compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1978-10-17 US disclosed
US-3989882-A Process for preparing an alternating copolymer of a conjugated vinyl compound and an olefinic unsaturated compound SUMITOMO CHEMICAL COMPANY, LIMITED (JA) 1976-11-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260139129-A1 Polyethylene Resin Composition MACF1, LBR, SMCHD1 ORAI1 4588/4885ORAI2 4366/4885ORAI3 4511/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.