⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL37779 | 0.67 | — | — | |
| SCHEMBL29129459 | 0.62 | — | — | |
| SCHEMBL1208220 | 0.62 | — | — | |
| SCHEMBL3389306 | 0.62 | — | — | |
| SCHEMBL21221329 | 0.62 | — | — | |
| SCHEMBL19948717 | 0.62 | — | — | |
| SCHEMBL28770740 | 0.59 | HRH3 (0.31) | — | |
| SCHEMBL79194 | 0.59 | — | — | |
| Fluoride SCHEMBL28867502 | 0.59 | MGLL (0.42) | — | |
| SCHEMBL15365152 | 0.46 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103965107-A | 2-aryl-substituted quinoline compounds and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2014-08-06 | — | — | CN | claimed |
| US-20200216434-A1 | BENZOFURAN UREAS OR CARBAMATES AND HETEROAROMATIC ANALOGUES THEREOF FOR USE IN THERAPY | EUROPEAN MOLECULAR BIOLOGY LABORATORY (DE) | 2020-07-09 | — | — | US | disclosed |
| CN-103965107-A | 2-aryl-substituted quinoline compounds and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2014-08-06 | — | — | CN | disclosed |
| CN-101903349-B | 4- (4-pyridinyl) -benzamides and their use as ROCK activity modulators | ABBOTT GMBH & CO KG | 2014-01-08 | — | — | CN | disclosed |
| CN-102076690-A | Protein kinase inhibitors | VERTEX PHARMA | 2011-05-25 | — | — | CN | disclosed |
| CN-102076691-A | Protein kinase inhibitors | VERTEX PHARMA | 2011-05-25 | — | — | CN | disclosed |
| CN-101903349-A | 4- (4-pyridinyl) -benzamides and their use as ROCK activity modulators | ABBOTT GMBH & CO KG | 2010-12-01 | — | — | CN | disclosed |
| CN-100577658-C | Quinazoline derivatives | ASTRAZENECA AB | 2010-01-06 | — | — | CN | disclosed |
| CN-1886399-A | Quinazoline derivatives | ASTRAZENECA AB (SE) | 2006-12-27 | — | — | CN | disclosed |