Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22769033 | 0.82 | EPHX2 (0.50) | EPHX2PPARGCYSLTR1 | |
| SCHEMBL22188906 | 0.82 | ELANE (0.44) | — | |
| SCHEMBL22188909 | 0.81 | PLA2G4A (0.52) | — | |
| SCHEMBL9586130 | 0.78 | — | — | |
| SCHEMBL7679479 | 0.76 | PLA2G4A (0.72) | — | |
| SCHEMBL9733925 | 0.76 | MEN1 (0.54) | EPHX2PPARGCYSLTR1 | |
| SCHEMBL9733072 | 0.75 | MEN1 (0.54) | EPHX2PPARGCYSLTR1 | |
| SCHEMBL9733232 | 0.75 | MEN1 (0.54) | EPHX2PPARGCYSLTR1 | |
| SCHEMBL9734376 | 0.75 | CYSLTR1 (0.56) | EPHX2PPARGCYSLTR1 | |
| SCHEMBL9733078 | 0.75 | MEN1 (0.54) | EPHX2PPARGCYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10752585-B2 | Process for the preparation of Zafirlukast and analogs thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-08-25 | — | — | US | disclosed |
| US-20200216390-A1 | PROCESS FOR THE PREPARATION OF ZAFIRLUKAST AND ANALOGS THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2020-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10752585-B2 | Process for the preparation of Zafirlukast and analogs thereof | CHUK, HRH2, CTSH | EPHX2 4144/4885PPARG 1439/4885CYSLTR1 1961/4885 |
| US-20200216390-A1 | PROCESS FOR THE PREPARATION OF ZAFIRLUKAST AND ANALOGS THEREOF | CHUK, CTSH, HRH2 | EPHX2 4367/4885PPARG 1592/4885CYSLTR1 2277/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.