SCHEMBL22190089

SCHEMBL22190089

CCCCCC(N(C(N)=O)C(CCCCC)[Si](OC)(OC)OC)[Si](OC)(OC)OC

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.39
GPR84 Q9NQS5 5/20 0.35
CA1 P00915 4/20 0.35
CA2 P00918 2/20 0.35
FFAR1 O14842 1/20 0.35
PRSS1 P07477 1/20 0.35
CTSG P08311 1/20 0.35
CTRB1 P17538 1/20 0.35
CMA1 P23946 1/20 0.35
LAP3 P28838 2/20 0.34
MAPT P10636 1/20 0.34
TP53 P04637 1/20 0.34
LCK P06239 1/20 0.34
PPARD Q03181 1/20 0.34
ZDHHC20 Q5W0Z9 1/20 0.34
ZDHHC2 Q9UIJ5 1/20 0.34
GRIK1 P39086 2/20 0.34
GRIK2 Q13002 2/20 0.34
SLC1A2 P43004 1/20 0.34
SLC1A1 P43005 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22190098 0.95 CA2 (0.40) ZDHHC7CA1CA2SLC1A2SLC1A1
SCHEMBL22190090 0.87 CHRM1 (0.31) CA1CA2
SCHEMBL22190086 0.85 TP53 (0.37) ZDHHC7GPR84CA1CA2FFAR1
SCHEMBL768197 0.80 ALOX15 (0.30)
SCHEMBL22190101 0.79 CA2 (0.39) CA1CA2TP53SLC1A2SLC1A1
SCHEMBL29760313 0.74 ZDHHC7 (0.43) ZDHHC7GPR84CA1CA2FFAR1
SCHEMBL16862751 0.72
SCHEMBL22190083 0.71 ALOX15 (0.31)
SCHEMBL8353866 0.71 GPR84 (0.39) GPR84CA1CA2FFAR1LAP3
Tromethamine SCHEMBL20981402 0.70 MEN1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11629235-B2 Urea-functionalized sol-gel KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-04-18 US claimed
US-20200216620-A1 UREA-FUNCTIONALIZED SOL-GEL KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2020-07-09 US claimed
US-11629235-B2 Urea-functionalized sol-gel KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2023-04-18 US disclosed
US-20200216620-A1 UREA-FUNCTIONALIZED SOL-GEL KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) 2020-07-09 US disclosed