Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.49 |
| ▸ | TNKS | O95271 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.41 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CTSG | P08311 | 1/20 | 0.39 |
| ▸ | CMA1 | P23946 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201218 | 1.00 | HDAC6 (0.49) | HDAC6HDAC1HDAC8TNKSHTR7 | |
| SCHEMBL10570931 | 0.86 | CYP19A1 (0.46) | HDAC6HDAC1HDAC8HTR7HDAC5 | |
| SCHEMBL3739324 | 0.85 | HDAC6 (0.54) | HDAC6HDAC1HDAC8TNKSHDAC5 | |
| SCHEMBL24282907 | 0.81 | PGR (0.47) | HDAC6HDAC1HDAC8TNKSHDAC5 | |
| SCHEMBL21104025 | 0.81 | PGR (0.47) | HDAC6HDAC1HDAC8TNKSHDAC5 | |
| SCHEMBL5591295 | 0.81 | LMNA (0.53) | HDAC6HDAC1HDAC8TNKSHDAC5 | |
| SCHEMBL19745745 | 0.80 | HDAC6 (0.53) | HDAC6HDAC1HDAC8HTR7HDAC5 | |
| SCHEMBL19745746 | 0.80 | HDAC6 (0.53) | HDAC6HDAC1HDAC8HTR7HDAC5 | |
| SCHEMBL13011721 | 0.79 | CETP (0.41) | HDAC6HDAC1HDAC8TNKSHTR7 | |
| SCHEMBL5428231 | 0.76 | TNKS (0.46) | HDAC6HDAC1HDAC8TNKSHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |