Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3336691 | 0.82 | MAPT (0.31) | ALDH1A1MAPT | |
| SCHEMBL29134461 | 0.80 | — | — | |
| SCHEMBL2342052 | 0.80 | — | — | |
| SCHEMBL3340143 | 0.79 | FFAR4 (0.32) | — | |
| SCHEMBL2347534 | 0.77 | — | — | |
| SCHEMBL11219131 | 0.77 | AHR (0.43) | ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL16858738 | 0.76 | KMT2A (0.35) | ALDH1A1NPC1MAPTRAB9A | |
| SCHEMBL8037350 | 0.74 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL15067557 | 0.73 | CA1 (0.37) | — | |
| SCHEMBL17529622 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8217055-B2 | Pyrido-pyrazine derivatives useful as herbicidal compounds | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-10 | — | — | US | claimed |
| EP-1909910-A1 | BENZIMIDAZOLE DERIVATIVES AS SIRTUIN MODULATORS | Sirtris Pharmaceuticals, Inc. (US) | 2008-04-16 | — | — | EP | claimed |
| EP-1910380-A1 | OXAZOLOPYRIDINE DERIVATIVES AS SIRTUIN MODULATORS | Sirtris Pharmaceuticals, Inc. (US) | 2008-04-16 | — | — | EP | claimed |
| WO-2007019417-A1 | OXAZOLOPYRIDINE DERIVATIVES AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | WO | claimed |
| US-20070037865-A1 | Silent Information Regulators; aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting , increased mitochondrial activity, inflammation, cancer, and/or flushing; increased lifespan specially in mutant sir2 strains; benzimidazo drivatives | SIRTRIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | US | claimed |
| WO-2007019416-A1 | BENZIMIDAZOLE DERIVATIVES AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | WO | claimed |
| US-20070037810-A1 | Sirtuin modulating compounds | SIRTIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | US | claimed |
| US-6436961-B1 | SUBSTANCE P RECEPTOR ANTAGONIST; 2-PHENYL-3-BENZYLAMINOPIPERIDINES | PFIZER INC | 2002-08-20 | — | — | US | claimed |
| EP-0062236-B1 | USE OF TRIAZOLE DERIVATIVES FOR COMBATING FUNGI | BASF Aktiengesellschaft (DE) | 1991-09-04 | — | — | EP | claimed |
| EP-0062236-A2 | Use of triazole derivatives for combating fungi | BASF Aktiengesellschaft (DE) | 1982-10-13 | — | — | EP | claimed |
| EP-2990404-B1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL CO (JP) | 2020-05-27 | — | — | EP | disclosed |
| EP-3029030-B1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | SUMITOMO CHEMICAL CO (JP) | 2019-09-04 | — | — | EP | disclosed |
| US-9867372-B2 | Tetrazolinone compound and use of same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-01-16 | — | — | US | disclosed |
| US-9512090-B2 | Tetrazolinone compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-12-06 | — | — | US | disclosed |
| US-20160159755-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2016-06-09 | — | — | US | disclosed |
| US-4368066-A | 1,3-Dioxan-5-yl-alkenyltriazoles, their preparation, their uses in regulating plant growth, and regulators containing these compounds | BASF AKTIENGESELLSCHAFT (DE) | 1983-01-11 | — | — | US | disclosed |
| EP-0062236-A2 | Use of triazole derivatives for combating fungi | BASF Aktiengesellschaft (DE) | 1982-10-13 | — | — | EP | disclosed |
| EP-0044407-A2 | 1,3-Dioxan-5-yl-alkyl triazoles, their preparation and their use as plant growth regulators | BASF Aktiengesellschaft (DE) | 1982-01-27 | — | — | EP | disclosed |
| EP-0043923-A2 | 1,3-Dioxan-5-yl-alkenyl triazoles, their preparation and their use as plant growth regulators | BASF Aktiengesellschaft (DE) | 1982-01-20 | — | — | EP | disclosed |
| US-4024144-A | SULFONIC ACID GROUPS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159755-A1 | TETRAZOLINONE COMPOUND AND USE THEREOF | CYP1A1, CASP1, TCOF1 | ALDH1A1 1480/4885GAA 4233/4885NPC1 3262/4885 |
| US-20070037865-A1 | Silent Information Regulators; aging or stress, diabetes, obesity, neurodegenerative diseases, cardiovascular disease, blood clotting , increased mitochondrial activity, inflammation, cancer, and/or flushing; increased lifespan specially in mutant sir2 strains; benzimidazo drivatives | SIRT2, SIRT1, SIRT3 | ALDH1A1 1903/4885GAA 1553/4885NPC1 3657/4885 |
| US-20070037810-A1 | Sirtuin modulating compounds | SIRT1, SIRT3, SIRT2 | ALDH1A1 1331/4885GAA 1262/4885NPC1 3313/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.