SCHEMBL221912

SCHEMBL221912

CCCCc1ccc(N(c2ccc(C3=CCC(c4ccccc4)(N(c4ccc(CCCC)cc4)c4ccc(C(C)C)cc4)C=C3)cc2)c2ccc(C(C)C)cc2)cc1

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
UCHL3 P15374 2/20 0.35
OPRL1 P41146 1/20 0.33
HSD11B1 P28845 1/20 0.32
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2348248 0.93 HSD11B1 (0.36) OPRL1HSD11B1
SCHEMBL223518 0.89 CNR2 (0.36) OPRL1HSD11B1
SCHEMBL2343295 0.87 HSD11B1 (0.32) HSD11B1
SCHEMBL221879 0.84 HSD11B1 (0.32) HSD11B1
SCHEMBL2770678 0.84 HSD11B1 (0.33) HSD11B1
SCHEMBL1304691 0.83 UCHL3 (0.37) UCHL3OPRL1HSD11B1HTR2A
SCHEMBL15324014 0.83 CNR2 (0.32) HSD11B1
SCHEMBL2268711 0.83 CNR2 (0.32) HSD11B1
SCHEMBL222680 0.82 HSD11B1 (0.33) HSD11B1
SCHEMBL4213712 0.80 KDM4E (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 156 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3309618-A1 POLYCARBONATE CONTAINING PHOTOCONDUCTORS Xerox Corporation (US) 2018-04-18 EP claimed
US-9851647-B1 Polycarbonate containing photoconductors XEROX CORPORATION (US) 2017-12-26 US claimed
US-20150261105-A1 BIPHENYL POLYCARBONATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2015-09-17 US claimed
US-9128392-B2 Polyarylatecarbonate containing photoconductors XEROX CORPORATION (US) 2015-09-08 US claimed
US-9069268-B2 Polyarylatecarbonate fluoropolymer containing photoconductors XEROX CORPORATION (US) 2015-06-30 US claimed
US-20150147690-A1 POLYARYLATECARBONATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2015-05-28 US claimed
US-20150079511-A1 POLYARYLATECARBONATE FLUOROPOLYMER CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2015-03-19 US claimed
US-20140356772-A1 TERPENE POLYCARBONATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2014-12-04 US claimed
US-8815481-B2 Imaging member with fluorosulfonamide-containing overcoat layer XEROX CORPORATION (US) 2014-08-26 US claimed
US-8785091-B1 Polyarylatecarbonate containing photoconductors XEROX CORPORATION (US) 2014-07-22 US claimed
US-7981578-B2 Additive containing photoconductors XEROX CORPORATION (US) 2011-07-19 US claimed
US-7981579-B2 Thiadiazole containing photoconductors XEROX CORPORATION (US) 2011-07-19 US claimed
US-7972756-B2 Ketal containing photoconductors XEROX CORPORATION (US) 2011-07-05 US claimed
US-7968262-B2 Bis(enylaryl)arylamine containing photoconductors XEROX CORPORATION (US) 2011-06-28 US claimed
US-7968263-B2 Amine phosphate containing photogenerating layer photoconductors XEROX CORPORATION (US) 2011-06-28 US claimed
US-20110151365-A1 POLYALKYLENE GLYCOL BENZOATE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2011-06-23 US claimed
US-7960079-B2 Phenazine containing photoconductors XEROX CORPORATION (US) 2011-06-14 US claimed
US-7960080-B2 Oxadiazole containing photoconductors XEROX CORPORATION (US) 2011-06-14 US claimed
US-7951514-B2 Polymer anticurl backside coating (ACBC) photoconductors XEROX CORPORATION (US) 2011-05-31 US claimed
US-7932006-B2 Photoconductors XEROX CORPORATION (US) 2011-04-26 US claimed