SCHEMBL2348248

SCHEMBL2348248

CCCCc1ccc(N(c2ccc(CCCC)cc2)c2ccc(C3=CCC(c4ccccc4)(N(c4ccc(CCCC)cc4)c4ccc(CCCC)cc4)C=C3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD11B1 P28845 2/20 0.36
NISCH Q9Y2I1 1/20 0.33
RARB P10826 1/20 0.33
OPRL1 P41146 1/20 0.32
BCHE P06276 1/20 0.31
POLB P06746 1/20 0.30
DHODH Q02127 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CHRM2 P08172 1/20 0.30
HTR1A P08908 1/20 0.30
ADRA2A P08913 1/20 0.30
CHRM1 P11229 1/20 0.30
DRD1 P21728 1/20 0.30
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
ADRA1A P35348 1/20 0.30
OPRM1 P35372 1/20 0.30
DRD3 P35462 1/20 0.30
SLC6A3 Q01959 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL223518 0.96 CNR2 (0.36) HSD11B1NISCHRARBOPRL1LTB4R2
SCHEMBL2343295 0.93 HSD11B1 (0.32) HSD11B1KCNH2
SCHEMBL221912 0.93 UCHL3 (0.35) HSD11B1OPRL1
SCHEMBL221879 0.91 HSD11B1 (0.32) HSD11B1LTB4R2
SCHEMBL2770678 0.90 HSD11B1 (0.33) HSD11B1LTB4R2
SCHEMBL15324014 0.89 CNR2 (0.32) HSD11B1LTB4R2
SCHEMBL2268711 0.89 CNR2 (0.32) HSD11B1LTB4R2
SCHEMBL222680 0.88 HSD11B1 (0.33) HSD11B1
SCHEMBL4213712 0.86 KDM4E (0.32)
SCHEMBL253619 0.85 HSD11B1 (0.31) HSD11B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7642029-B2 Imaging member XEROX CORPORATION (US) 2010-01-05 US claimed
US-20070172749-A1 Imaging member XEROX CORPORATION 2007-07-26 US claimed
US-8877413-B2 Flexible imaging members comprising improved ground strip XEROX CORPORATION (US) 2014-11-04 US disclosed
US-20130052576-A1 FLEXIBLE IMAGING MEMBERS COMPRISING IMPROVED GROUND STRIP XEROX CORPORATION (US) 2013-02-28 US disclosed
US-8343700-B2 Imaging members having stress/strain free layers XEROX CORPORATION (US) 2013-01-01 US disclosed
US-8232030-B2 Curl-free imaging members with a slippery surface XEROX CORPORATION (US) 2012-07-31 US disclosed
US-20110256474-A1 IMAGING MEMBERS HAVING STRESS/STRAIN FREE LAYERS XEROX CORPORATION (US) 2011-10-20 US disclosed
US-20110229808-A1 CURL-FREE IMAGING MEMBERS WITH A SLIPPERY SURFACE XEROX CORPORATION (US) 2011-09-22 US disclosed
US-20110207038-A1 SLIPPERY SURFACE IMAGING MEMBERS XEROX CORPORATION (US) 2011-08-25 US disclosed
US-7829252-B2 Imaging member XEROX CORPORATION (US) 2010-11-09 US disclosed
US-7642029-B2 Imaging member XEROX CORPORATION (US) 2010-01-05 US disclosed
US-7611811-B2 Imaging member XEROX CORPORATION (US) 2009-11-03 US disclosed
US-7538175-B2 Phenolic hole transport polymers XEROX CORPORATION (US) 2009-05-26 US disclosed
US-7527903-B2 Imaging member XEROX CORPORATION (US) 2009-05-05 US disclosed
US-20070172749-A1 Imaging member XEROX CORPORATION 2007-07-26 US disclosed
US-20070148572-A1 Imaging member XEROX CORPORATION 2007-06-28 US disclosed
US-20070099101-A1 Imaging member XEROX CORPORATION 2007-05-03 US disclosed
US-20070087276-A1 Phenolic hole transport polymers XEROX CORPORATON. 2007-04-19 US disclosed
EP-1775637-A1 Phenolic hole transport polymers Xerox Corporation (US) 2007-04-18 EP disclosed
US-20070054208-A1 Imaging member XEROX CORPORATION 2007-03-08 US disclosed