SCHEMBL2219161

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3655693	0.89	ALDH1A1 (0.53)	ALDH1A1GABRA5NPSR1PKMTDP1
	SCHEMBL2218827	0.89	ALDH1A1 (0.53)	ALDH1A1GABRA5NPSR1PKMTDP1
	SCHEMBL14438335	0.87	ALDH1A1 (0.59)	ALDH1A1GABRA5NPSR1PKMTDP1
	SCHEMBL2217114	0.81	GABRA5 (0.48)	ALDH1A1GABRA5NPSR1PKMTDP1
	SCHEMBL5018927	0.76	PTGS1 (0.54)	ALDH1A1GABRA5NPSR1PKMPTGS1
	SCHEMBL17040356	0.76	ALDH1A1 (0.67)	ALDH1A1GABRA5NPSR1PKMKDM4E
	SCHEMBL17037447	0.74	ALDH1A1 (0.65)	ALDH1A1GABRA5NPSR1PKMKDM4E
	SCHEMBL256699	0.74	PTGS1 (0.59)	ALDH1A1GABRA5NPSR1PKMPTGS1
	SCHEMBL286436	0.72	PTGS1 (0.58)	ALDH1A1GABRA5NPSR1PKMTDP1
	SCHEMBL107436	0.72	PTGS1 (0.58)	ALDH1A1GABRA5NPSR1PKMKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.