SCHEMBL22192527

SCHEMBL22192527

c1ccc(-c2cccc(-n3c4ccc5c6ccccc6oc5c4c4ccc5c(c6ccccc6n5-c5ccccc5)c43)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.36
ATM Q13315 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 4/20 0.36
POLB P06746 2/20 0.36
KMT2A Q03164 2/20 0.36
MEN1 O00255 1/20 0.36
TSHR P16473 1/20 0.36
BRCA1 P38398 1/20 0.36
HSD17B10 Q99714 1/20 0.36
RXFP1 Q9HBX9 3/20 0.33
PPARG P37231 2/20 0.33
NR2E3 Q9Y5X4 2/20 0.33
NCOR2 Q9Y618 2/20 0.33
ALOX5 P09917 2/20 0.32
LMNA P02545 2/20 0.31
PLA2G2A P14555 2/20 0.30
PLA2G4A P47712 2/20 0.30
IL1R1 P14778 1/20 0.30
CA12 O43570 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18618894 1.00 KDM4E (0.36) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL18620493 0.99 ALDH1A1 (0.34) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL18619028 0.98 ALDH1A1 (0.35) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL18619034 0.98 ALDH1A1 (0.35) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL18619032 0.95 ALDH1A1 (0.33) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL22192667 0.95 ALDH1A1 (0.33) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL18618971 0.95 ALDH1A1 (0.33) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL18619004 0.95 ALDH1A1 (0.33) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL18619006 0.95 PLA2G2A (0.33) KDM4EATML3MBTL1ALDH1A1POLB
SCHEMBL18620342 0.95 ALDH1A1 (0.34) KDM4EATML3MBTL1ALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10703762-B2 Compound, material for organic electroluminescence device, organic electroluminescence device and electronic apparatus IDEMITSU KOSAN CO., LTD. (JP) 2020-07-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10703762-B2 Compound, material for organic electroluminescence device, organic electroluminescence device and electronic apparatus PIEZO1, OR10J3, EPCAM KDM4E 3529/4885ATM 1283/4885L3MBTL1 2738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.