Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | AIP | O00170 | 1/20 | 0.43 |
| ▸ | SGTA | O43765 | 1/20 | 0.43 |
| ▸ | TOMM70 | O94826 | 1/20 | 0.43 |
| ▸ | STIP1 | P31948 | 1/20 | 0.43 |
| ▸ | PPP5C | P53041 | 1/20 | 0.43 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.43 |
| ▸ | PPID | Q08752 | 1/20 | 0.43 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.43 |
| ▸ | FKBP8 | Q14318 | 1/20 | 0.43 |
| ▸ | TOMM34 | Q15785 | 1/20 | 0.43 |
| ▸ | DNAJC7 | Q99615 | 1/20 | 0.43 |
| ▸ | AIPL1 | Q9NZN9 | 1/20 | 0.43 |
| ▸ | STUB1 | Q9UNE7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.42 |
| ▸ | MAPT | P10636 | 8/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19136021 | 0.81 | ALDH1A1 (0.55) | CYP1A2POLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL23728786 | 0.81 | ALDH1A1 (0.55) | CYP1A2POLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL15281425 | 0.81 | ALDH1A1 (0.55) | CYP1A2POLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL18551518 | 0.80 | ALDH1A1 (0.52) | CYP1A2POLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL20831849 | 0.79 | CYP1A2 (0.38) | CYP1A2POLBCYP2C9CYP2C19AIP | |
| SCHEMBL20831148 | 0.74 | SMN1; SMN2 (0.61) | POLBAIPSGTATOMM70STIP1 | |
| SCHEMBL20831154 | 0.71 | ABCC1 (0.42) | CYP1A2POLBCYP2C9CYP2C19AIP | |
| SCHEMBL22193209 | 0.69 | ALDH1A1 (0.40) | AIPSGTATOMM70STIP1PPP5C | |
| SCHEMBL14191229 | 0.68 | ALDH1A1 (0.47) | CYP1A2POLBCYP2C9CYP2C19AIP | |
| SCHEMBL31498681 | 0.68 | ALDH1A1 (0.57) | CYP1A2POLBCYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200216464-A1 | NEW COMPOUND USEFUL IN THE MANUFACTURE OF MEDICAMENTS | HOFFMANN-LA ROCHE INC. (US) | 2020-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200216464-A1 | NEW COMPOUND USEFUL IN THE MANUFACTURE OF MEDICAMENTS | DPM1, MRGPRX2, COXFA4L2 | CYP1A2 379/4885POLB 3487/4885CYP2C9 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.