Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.85 |
| ▸ | JUN | P05412 | 1/20 | 0.85 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.57 |
| ▸ | STAT3 | P40763 | 1/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.57 |
| ▸ | RELA | Q04206 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | JAK2 | O60674 | 1/20 | 0.56 |
| ▸ | VCP | P55072 | 1/20 | 0.55 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3207352 | 0.92 | NFKB1 (1.00) | NFKB1JUNALOX5CYP1A2CYP2D6 | |
| SCHEMBL3207347 | 0.92 | NFKB1 (1.00) | NFKB1JUNALOX5CYP1A2CYP2D6 | |
| SCHEMBL20144408 | 0.90 | JUN (0.69) | NFKB1JUNALOX5KDM4ESMN1; SMN2 | |
| SCHEMBL31256668 | 0.88 | JUN (0.68) | NFKB1JUNALOX5KDM4ESMN1; SMN2 | |
| SCHEMBL2294213 | 0.88 | JUN (0.68) | NFKB1JUNALOX5KDM4ESMN1; SMN2 | |
| SCHEMBL2294216 | 0.88 | JUN (0.68) | NFKB1JUNALOX5KDM4ESMN1; SMN2 | |
| SCHEMBL7017036 | 0.87 | JUN (0.66) | NFKB1JUNALOX5KDM4ESMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8830740 | 0.87 | JUN (0.66) | NFKB1JUNALOX5KDM4ESMN1; SMN2 | |
| SCHEMBL5934912 | 0.87 | JUN (0.66) | NFKB1JUNALOX5KDM4ESMN1; SMN2 | |
| SCHEMBL30964227 | 0.87 | JUN (0.66) | NFKB1JUNALOX5NFE2L2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130053594-A1 | METHODS OF MAKING SELF-HEALING POLYMER AND GEL COMPOSITIONS | THE UNIVERSITY OF CHICAGO (US) | 2013-02-28 | — | — | US | disclosed |
| WO-2011084710-A1 | METHODS OF MAKING SELF-HEALING POLYMER AND GEL COMPOSITIONS | THE UNIVERSITY OF CHICAGO (US) | 2011-07-14 | — | — | WO | disclosed |
| EP-0232679-B1 | SYNTHETIC ORGANIC POLYMERS FOR THE SELECTIVE FLOCCULATION OF TITANIUM AND IRON ORES | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1990-07-25 | — | — | EP | disclosed |
| US-4698171-A | Synthetic organic polymers for the selective flocculation of titanium and iron ores | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1987-10-06 | — | — | US | disclosed |
| EP-0232679-A1 | Synthetic organic polymers for the selective flocculation of titanium and iron ores | CONSIGLIO NAZIONALE DELLE RICERCHE (IT) | 1987-08-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053594-A1 | METHODS OF MAKING SELF-HEALING POLYMER AND GEL COMPOSITIONS | PCNA, PUF60, PPIG | NFKB1 1060/4885JUN 1162/4885ALOX5 659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.