Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KLF10 | Q13118 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12674534 | 0.94 | ALOX5 (0.57) | ALOX5ELANEPTGS1SRD5A1AKR1C3 | |
| SCHEMBL29710717 | 0.94 | ALOX5 (0.57) | ALOX5ELANEPTGS1SRD5A1AKR1C3 | |
| SCHEMBL26119063 | 0.90 | ALOX5 (0.52) | ALOX5ELANEPTGS1SRD5A1AKR1C3 | |
| SCHEMBL804638 | 0.89 | ALOX5 (0.59) | ALOX5ELANEPTGS1SRD5A1AKR1C3 | |
| SCHEMBL22421389 | 0.86 | ALOX5 (0.51) | ALOX5ELANEPTGS1SRD5A1AKR1C3 | |
| SCHEMBL14048479 | 0.85 | ALOX5 (0.50) | ALOX5ELANEPTGS1SRD5A1AKR1C3 | |
| SCHEMBL15500145 | 0.84 | ELANE (0.44) | ALOX5ELANEPTGS1KMT2AMAPT | |
| SCHEMBL13864923 | 0.84 | ELANE (0.45) | ALOX5ELANEPTGS1KMT2AMAPT | |
| SCHEMBL9186206 | 0.83 | ELANE (0.47) | ALOX5ELANEPTGS1KMT2AMAPT | |
| SCHEMBL12580079 | 0.83 | GABRA1 (0.47) | ALOX5PTGS1MAPTKLF10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3492444-B1 | METHODS OF MAKING STABLE AND THERMALLY POLYMERIZABLE VINYL, AMINO OR OLIGOMERIC PHENOXY BENZOCYCLOBUTENE MONOMERS WITH IMPROVED CURING KINETICS | ROHM & HAAS ELECT MAT (US) | 2020-07-08 | — | — | EP | disclosed |