Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | JUN | P05412 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12674534 | 0.95 | ALOX5 (0.57) | ALOX5PTGS1ELANEGABRA1GABRB2 | |
| SCHEMBL29710717 | 0.95 | ALOX5 (0.57) | ALOX5PTGS1ELANEGABRA1GABRB2 | |
| SCHEMBL22421389 | 0.90 | ALOX5 (0.51) | ALOX5PTGS1ELANEGABRA1GABRB2 | |
| SCHEMBL26119063 | 0.89 | ALOX5 (0.52) | ALOX5PTGS1ELANEGABRA1GABRB2 | |
| SCHEMBL22197873 | 0.89 | ALOX5 (0.52) | ALOX5PTGS1ELANETSHRMEN1 | |
| SCHEMBL238989 | 0.88 | GABRA1 (0.52) | ALOX5PTGS1GABRA1GABRB2GABRA5 | |
| SCHEMBL14048479 | 0.86 | ALOX5 (0.50) | ALOX5PTGS1ELANEGABRA1GABRB2 | |
| SCHEMBL12438742 | 0.85 | TSHR (0.44) | ALOX5PTGS1TSHRJUNNFKB1 | |
| SCHEMBL9186206 | 0.84 | ELANE (0.47) | ALOX5PTGS1ELANEGABRA1GABRB2 | |
| SCHEMBL11071323 | 0.83 | ELANE (0.48) | ALOX5PTGS1ELANEPTPN1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426532-B2 | Polycarbonate graft copolymers | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2013-04-23 | — | — | US | disclosed |
| US-20120071606-A1 | POLYCARBONATE GRAFT COPOLYMERS | SABIC INNOVATIVE PLASTICS IP B.V. (NL) | 2012-03-22 | — | — | US | disclosed |