SCHEMBL22197963

SCHEMBL22197963

CC(C)(COC(C)(C)O)CC(=O)NCCNC=O

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22060943 0.81 MCL1 (0.38) LMNA
SCHEMBL22170823 0.80
SCHEMBL20613631 0.79 ADH1B (0.34) LMNA
SCHEMBL22139744 0.79
SCHEMBL19827670 0.78 TDP1 (0.39)
SCHEMBL22139654 0.78 ECE1 (0.41)
SCHEMBL22139735 0.71 L3MBTL1 (0.31)
SCHEMBL22170791 0.71 PIK3CD (0.31)
SCHEMBL22170797 0.71 PIK3CD (0.31)
SCHEMBL25760592 0.70 PIK3CD (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3906225-B1 PANTOTHENAMIDE ANALOGUES MEDICINES FOR MALARIA VENTURE MMV (CH) 2023-07-05 EP disclosed
WO-2020141155-A1 PANTOTHENAMIDE ANALOGUES MMV MEDICINES FOR MALARIA VENTURE (CH) 2020-07-09 WO disclosed