Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1B | P00325 | 3/20 | 0.34 |
| ▸ | ADH1A | P07327 | 3/20 | 0.34 |
| ▸ | ADH7 | P40394 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | ADH4 | P08319 | 1/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20613635 | 0.79 | NAAA (0.32) | MEN1KMT2ANAAA | |
| SCHEMBL20613663 | 0.79 | MEN1 (0.50) | MEN1KMT2ANAAA | |
| SCHEMBL22197963 | 0.79 | LMNA (0.30) | LMNA | |
| SCHEMBL22236865 | 0.79 | CNR1 (0.37) | LMNAMEN1KMT2ANAAA | |
| SCHEMBL20613710 | 0.77 | MCL1 (0.44) | LMNAMEN1KMT2AEPHX1NAAA | |
| SCHEMBL20613667 | 0.76 | CASP2 (0.48) | KMT2ANAAA | |
| SCHEMBL19827537 | 0.76 | PTGS1 (0.49) | MEN1KMT2ANAAA | |
| SCHEMBL17718098 | 0.74 | ECE1 (0.47) | KMT2A | |
| SCHEMBL20613639 | 0.74 | NAAA (0.47) | MEN1KMT2ANAAA | |
| SCHEMBL22336844 | 0.73 | ALDH1A1 (0.37) | ADH1BADH1AADH7LMNAADH1C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3215496-B1 | PANTOTHENAMIDE ANALOGUES | RADBOUD UNIV MEDISCH CENTRUM (NL) | 2019-01-02 | — | — | EP | disclosed |