Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MLYCD | O95822 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22199646 | 0.79 | ALDH1A1 (0.36) | ALDH1A1HPGDSIGMAR1L3MBTL1 | |
| SCHEMBL19155366 | 0.78 | ALDH1A1 (0.33) | ALDH1A1HPGDPOLBTDP1 | |
| SCHEMBL14201301 | 0.77 | KCNQ3 (0.39) | ALDH1A1HPGDMLYCDPOLBGAA | |
| SCHEMBL13612708 | 0.77 | ALDH1A1 (0.48) | ALDH1A1HPGDMLYCDNAMPTCA12 | |
| SCHEMBL12155306 | 0.74 | MLYCD (0.42) | ALDH1A1HPGDMLYCDNAMPTCA12 | |
| SCHEMBL26043609 | 0.74 | DNM1 (0.56) | ALDH1A1TSHR | |
| SCHEMBL1373081 | 0.73 | ALDH1A1 (0.57) | ALDH1A1HPGDCA12CA2CA9 | |
| SCHEMBL2838599 | 0.73 | ALDH1A1 (0.47) | ALDH1A1HPGDMLYCDPOLBL3MBTL1 | |
| SCHEMBL22799902 | 0.72 | ALDH1A1 (0.34) | ALDH1A1HPGDCA12CA2CA9 | |
| SCHEMBL23889729 | 0.71 | ALDH1A1 (0.43) | ALDH1A1HPGDMLYCDNAMPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11358988-B2 | Immunomodulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2022-06-14 | — | — | US | disclosed |
| US-20200216498-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11358988-B2 | Immunomodulators | CD74, ICOS, HAVCR2 | ALDH1A1 1217/4885HPGD 1110/4885MLYCD 2578/4885 |
| US-20200216498-A1 | IMMUNOMODULATORS | CD74, ICOS, HAVCR2 | ALDH1A1 1217/4885HPGD 1110/4885MLYCD 2578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.