SCHEMBL22200033

SCHEMBL22200033

c1ccc(-c2ccc(-c3nc4ccccc4nc3-n3c4ccccc4c4c5ccccc5c5c6ccccc6oc5c43)cc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.38
CASP1 P29466 1/20 0.38
MEN1 O00255 3/20 0.36
KMT2A Q03164 3/20 0.36
CSF1R P07333 1/20 0.36
PDGFRB P09619 1/20 0.36
MAPT P10636 1/20 0.36
KIT P10721 1/20 0.36
FLT3 P36888 1/20 0.36
HDAC6 Q9UBN7 1/20 0.36
HRH4 Q9H3N8 1/20 0.36
DHODH Q02127 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
KDM4E B2RXH2 2/20 0.34
GAA P10253 2/20 0.34
ALDH1A1 P00352 1/20 0.34
HPGD P15428 1/20 0.34
PTGER1 P34995 1/20 0.34
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16582318 0.98 HSD17B10 (0.40) HSD17B10CASP1MEN1KMT2ACSF1R
SCHEMBL19986144 0.94 HSD17B10 (0.37) HSD17B10CASP1MEN1KMT2ACSF1R
SCHEMBL19986204 0.91 HSD17B10 (0.38) HSD17B10CASP1MEN1KMT2ACSF1R
SCHEMBL22199930 0.90 MAPT (0.36) HSD17B10CASP1MEN1KMT2ACSF1R
SCHEMBL22199796 0.89 MEN1 (0.36) HSD17B10MEN1KMT2ACSF1RPDGFRB
SCHEMBL22200034 0.88 NPC1 (0.33) DHODHNPC1RAB9A
SCHEMBL22199929 0.88 MEN1 (0.33) MEN1KMT2ACSF1RPDGFRBMAPT
SCHEMBL22200030 0.88 PTGER1 (0.33) MEN1KMT2ACSF1RPDGFRBMAPT
SCHEMBL22199774 0.88 MEN1 (0.37) HSD17B10MEN1KMT2ACSF1RPDGFRB
SCHEMBL19544180 0.87 HSD17B10 (0.37) HSD17B10CASP1MEN1KMT2ACSF1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200216392-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2020-07-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200216392-A1 A PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME TERF2, PIEZO1, TERT HSD17B10 4188/4885CASP1 735/4885MEN1 1732/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.