Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 9/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22200412 | 0.84 | STING1 (0.64) | STING1 | |
| SCHEMBL22200458 | 0.83 | STING1 (0.54) | STING1ALDH1A1LMNA | |
| SCHEMBL22200409 | 0.82 | STING1 (0.44) | STING1 | |
| SCHEMBL22200410 | 0.82 | STING1 (0.53) | STING1ALDH1A1LMNA | |
| SCHEMBL22200414 | 0.82 | STING1 (0.47) | STING1ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL24175221 | 0.79 | STING1 (0.63) | STING1 | |
| SCHEMBL24175795 | 0.78 | STING1 (0.53) | STING1ALDH1A1L3MBTL1 | |
| SCHEMBL24175604 | 0.78 | STING1 (0.54) | STING1ALDH1A1 | |
| SCHEMBL24175209 | 0.77 | STING1 (0.54) | STING1ALDH1A1 | |
| SCHEMBL24175222 | 0.77 | STING1 (0.54) | STING1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3907221-A1 | FLUORINE-CONTAINING SUBSTITUTED BENZOTHIOPHENE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-11-10 | — | — | EP | disclosed |
| WO-2020140894-A1 | FLUORINE-CONTAINING SUBSTITUTED BENZOTHIOPHENE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 中国科学院上海药物研究所 | 2020-07-09 | — | — | WO | disclosed |