Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 17/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24175604 | 0.91 | STING1 (0.54) | STING1POLBFFAR4 | |
| SCHEMBL22200458 | 0.89 | STING1 (0.54) | STING1SMN1; SMN2 | |
| SCHEMBL22200410 | 0.88 | STING1 (0.53) | STING1SMN1; SMN2 | |
| SCHEMBL24175099 | 0.88 | STING1 (0.50) | STING1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL24175193 | 0.87 | STING1 (0.48) | STING1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL24175179 | 0.85 | STING1 (0.47) | STING1POLBMAPK1SMN1; SMN2 | |
| SCHEMBL22200404 | 0.84 | STING1 (0.48) | STING1 | |
| SCHEMBL24175195 | 0.84 | STING1 (0.54) | STING1 | |
| SCHEMBL24175062 | 0.83 | STING1 (0.52) | STING1 | |
| SCHEMBL24175221 | 0.83 | STING1 (0.63) | STING1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022002077-A1 | ARYL AROMATIC HETEROCYCLIC DERIVATIVE AND PREPARATION METHOD THEREFOR AND USE THEREOF | 上海海和药物研究开发股份有限公司 | 2022-01-06 | — | — | WO | disclosed |
| EP-3907221-A1 | FLUORINE-CONTAINING SUBSTITUTED BENZOTHIOPHENE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) | 2021-11-10 | — | — | EP | disclosed |
| WO-2020140894-A1 | FLUORINE-CONTAINING SUBSTITUTED BENZOTHIOPHENE COMPOUND, AND PHARMACEUTICAL COMPOSITION AND APPLICATION THEREOF | 中国科学院上海药物研究所 | 2020-07-09 | — | — | WO | disclosed |