SCHEMBL2220085

SCHEMBL2220085

C[Si](C)(Cl)CC(CCl)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
TSHR P16473 1/20 0.34
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
AOC3 Q16853 5/20 0.34
GABBR2 O75899 2/20 0.34
GABBR1 Q9UBS5 2/20 0.34
TAAR1 Q96RJ0 4/20 0.33
HTR2A P28223 1/20 0.33
HRH1 P35367 1/20 0.33
CYP2D6 P10635 1/20 0.33
RIPK1 Q13546 1/20 0.32
KDM4E B2RXH2 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2100574 0.88 TSHR (0.34) LMNATSHRSLC6A2SLC6A4SLC6A3
SCHEMBL2101611 0.83 TSHR (0.37) TSHRSLC6A2SLC6A4SLC6A3AOC3
SCHEMBL2543705 0.79 EPHX1 (0.34) TSHRSLC6A2SLC6A4SLC6A3GABBR2
SCHEMBL18662207 0.79 HRH1 (0.43) LMNATSHRSLC6A2SLC6A4SLC6A3
SCHEMBL30007259 0.78 CYP2D6 (0.32) TSHRSLC6A2SLC6A4SLC6A3TAAR1
SCHEMBL5598365 0.78 TSHR (0.48) LMNATSHRGABBR2GABBR1TAAR1
SCHEMBL485620 0.77 SMN1; SMN2 (0.33) LMNATSHRSLC6A2SLC6A4SLC6A3
SCHEMBL2881080 0.74 LMNA (0.33) LMNATSHRSLC6A2SLC6A4SLC6A3
SCHEMBL2237751 0.74 LMNA (0.48) LMNATSHRAOC3TAAR1HTR2A
SCHEMBL6686932 0.71 AOC3 (0.43) LMNATSHRAOC3TAAR1HTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 152 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 US disclosed
US-12173166-B2 Articles including surface coatings and methods to produce them MAXTERIAL, INC. (US) 2024-12-24 US disclosed
US-12109812-B2 Ink jet printing method and ink jet printing apparatus SEIKO EPSON CORPORATION (JP) 2024-10-08 US disclosed
US-20230295827-A1 COATINGS AND COATED SURFACES INCLUDING LOW-SURFACE ENERGY INORGANIC PARTICLES MAXTERIAL INC (US) 2023-09-21 US disclosed
CN-114055975-B Ink jet recording method and ink jet recording apparatus 精工爱普生株式会社 2023-05-12 CN disclosed
US-11542621-B1 Coatings and coated surfaces including low-surface energy inorganic particles MAXTERIAL, INC. (US) 2023-01-03 US disclosed
CN-114055975-A Ink jet recording method and ink jet recording apparatus 精工爱普生株式会社 2022-02-18 CN disclosed
US-20220032618-A1 Ink Jet Printing Method And Ink Jet Printing Apparatus SEIKO EPSON CORPORATION (JP) 2022-02-03 US disclosed
EP-3067395-B1 ULTRAVIOLET RADIATION-CURABLE COMPOSITION, AND RECORDED MATTER SEIKO EPSON CORP (JP) 2020-10-28 EP disclosed
US-10759119-B2 Three dimensional mold object manufacturing apparatus, method for manufacturing three dimensional mold object, and three dimensional mold object SEIKO EPSON CORPORATION (JP) 2020-09-01 US disclosed
US-20060052623-A1 Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance CHISSO CORPORATION (JP) 2006-03-09 US disclosed
US-20060019034-A1 Process for producing chemical adsorption film and chemical adsorption film SEIKO EPSON CORPORATION (JP) 2006-01-26 US disclosed
US-20050287392-A1 Organic electroluminescent device, method for producing the same, and electronic apparatus SEIKO EPSON CORPORATION (JP) 2005-12-29 US disclosed
CN-1713787-A Organic electroluminescent device, method for producing the same, and electronic apparatus SEIKO EPSON CORP (JP) 2005-12-28 CN disclosed
US-20040204556-A1 Atom or group transfer radical polymerization MATYJASZEWSKI KRZYSZTOF (US) 2004-10-14 US disclosed
US-6541580-B1 Controlling living polymerization via e.g. polyphosphazene initiators CARNEGIE MELLON UNIVERSITY 2003-04-01 US disclosed
US-6512060-B1 Contacting at least one first molecule comprising one or more radically transferable atoms or groups, and at least one second molecule comprising one or more radically transferable atoms or groups with a system comprising: a transition metal, CARNEGIE MELLON UNIVERSITY 2003-01-28 US disclosed
EP-0966489-A4 IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION UNIV CARNEGIE MELLON (US) 2002-03-06 EP disclosed
EP-0966489-A1 IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION CARNEGIE MELLON UNIVERSITY (US) 1999-12-29 EP disclosed
WO-1998040415-A1 IMPROVEMENTS IN ATOM OR GROUP TRANSFER RADICAL POLYMERIZATION CARNEGIE MELLON UNIVERSITY (US) 1998-09-17 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060052623-A1 Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance STS, PFAS, POLQ LMNA 2213/4885TSHR 2188/4885SLC6A2 4727/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.