SCHEMBL2543705

SCHEMBL2543705

CO[Si](C)(CC(CCl)c1ccccc1)OC

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.34
MAPT P10636 2/20 0.34
GAA P10253 1/20 0.34
GABBR2 O75899 1/20 0.33
GABBR1 Q9UBS5 1/20 0.33
CYP2D6 P10635 2/20 0.33
CYP1A2 P05177 1/20 0.33
PKM P14618 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ALDH1A1 P00352 2/20 0.32
KMT2A Q03164 1/20 0.32
SLC6A2 P23975 2/20 0.31
SLC6A4 P31645 2/20 0.31
SLC6A3 Q01959 2/20 0.31
POLB P06746 1/20 0.31
TAAR1 Q96RJ0 2/20 0.31
TSHR P16473 1/20 0.31
PBRM1 Q86U86 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL485620 0.84 SMN1; SMN2 (0.33) EPHX1MAPTGAACYP2D6CYP1A2
SCHEMBL1197511 0.83 EPHX1 (0.36) EPHX1MAPTGAAGABBR2GABBR1
SCHEMBL2220085 0.79 LMNA (0.38) GABBR2GABBR1CYP2D6SLC6A2SLC6A4
SCHEMBL2100574 0.79 TSHR (0.34) GABBR2GABBR1CYP2D6CYP1A2PKM
SCHEMBL18662219 0.79 HRH1 (0.40) EPHX1KMT2ASLC6A2SLC6A4SLC6A3
SCHEMBL30007259 0.77 CYP2D6 (0.32) EPHX1CYP2D6CYP1A2PKMSMN1; SMN2
SCHEMBL4196297 0.76 TAAR1 (0.47) ALDH1A1KMT2ATAAR1
SCHEMBL2101611 0.75 TSHR (0.37) GABBR2GABBR1CYP2D6CYP1A2PKM
SCHEMBL2881080 0.74 LMNA (0.33) MAPTCYP2D6CYP1A2PKMSMN1; SMN2
SCHEMBL5598365 0.73 TSHR (0.48) GABBR2GABBR1CYP2D6CYP1A2PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120202247-A Silane compound and composition containing same 昕特玛私人有限公司 2025-06-24 CN claimed
US-12554198-B2 Functional hydrogen silsesquioxane resins and the use thereof PIBOND OY (FI) 2026-02-17 US disclosed
US-20250326936-A1 ARTICLES INCLUDING SURFACE COATINGS AND METHODS TO PRODUCE THEM MAXTERIAL INC (US) 2025-10-23 US disclosed
CN-120202247-A Silane compound and composition containing same 昕特玛私人有限公司 2025-06-24 CN disclosed
US-12173166-B2 Articles including surface coatings and methods to produce them MAXTERIAL, INC. (US) 2024-12-24 US disclosed
US-20230295827-A1 COATINGS AND COATED SURFACES INCLUDING LOW-SURFACE ENERGY INORGANIC PARTICLES MAXTERIAL INC (US) 2023-09-21 US disclosed
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same JSI SILICONE CO. (KR) 2023-06-27 US disclosed
US-11542621-B1 Coatings and coated surfaces including low-surface energy inorganic particles MAXTERIAL, INC. (US) 2023-01-03 US disclosed
EP-4106913-A1 COMPOSITIONS, METHODS AND SYSTEMS FOR SAMPLE PROCESSING 10X Genomics, Inc. (US) 2022-12-28 EP disclosed
CN-115461143-A Compositions, methods, and systems for sample processing 10X基因组学有限公司 2022-12-09 CN disclosed
US-20160159660-A1 SILICON CONTAINING POLYMER FLOCCULANTS CYTEC INDUSTRIES INC. (US) 2016-06-09 US disclosed
US-20150191646-A1 FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME BAKER HUGHES INCORPORATED (US) 2015-07-09 US disclosed
US-9012377-B2 Functionalized silicate nanoparticle composition, removing and exfoliating asphaltenes with same BAKER HUGHES INCORPORATED (US) 2015-04-21 US disclosed
US-20140187449-A1 FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME BAKER HUGHES INCORPORATED (US) 2014-07-03 US disclosed
WO-2014106007-A1 FUNCTIONALIZED SILICATE NANOPARTICLE COMPOSITION, REMOVING AND EXFOLIATING ASPHALTENES WITH SAME BAKER HUGHES INCORPORATED (US) 2014-07-03 WO disclosed
US-8501326-B2 Wax replacement specialty formulated corrugating adhesive HENKEL CORPORATION (US) 2013-08-06 US disclosed
US-20110259945-A1 WAX REPLACEMENT SPECIALTY FORMULATED CORRUGATING ADHESIVE HENKEL AG & CO. KGAA (DE) 2011-10-27 US disclosed
WO-2010080973-A2 WAX REPLACEMENT SPECIALTY FORMULATED CORRUGATING ADHESIVE HENKEL CORPORATION (US) 2010-07-15 WO disclosed
WO-2010054134-A1 WATERBORNE ADHESIVE HENKEL CORPORATION (US) 2010-05-14 WO disclosed
US-20100119741-A1 Waterborne Adhesive HENKEL CORPORATION 2010-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11685702-B2 Method for producing arene compounds and arene compounds produced by the same PFAS, FRK, AGPAT2 EPHX1 2087/4885MAPT 3934/4885GAA 1518/4885
US-12554198-B2 Functional hydrogen silsesquioxane resins and the use thereof MACF1, RTF1, ERCC4 EPHX1 216/4885MAPT 4205/4885GAA 1415/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.