Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2214585 | 0.88 | KMT2A (0.56) | MEN1KMT2APTGER4KDM4EALDH1A1 | |
| SCHEMBL2217196 | 0.86 | MEN1 (0.43) | MEN1KMT2ACTSDGPR35CYP1A2 | |
| SCHEMBL2216231 | 0.85 | PTGER4 (0.54) | MEN1KMT2APTGER4SMN1; SMN2KDM4E | |
| SCHEMBL2215283 | 0.83 | CYP19A1 (0.49) | MEN1KMT2ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2215558 | 0.81 | CNR2 (0.50) | KDM4EALDH1A1 | |
| SCHEMBL2213030 | 0.79 | SIGMAR1 (0.45) | PTGER4 | |
| SCHEMBL2216044 | 0.79 | ALDH1A1 (0.42) | MEN1KMT2APTGER4SMN1; SMN2KDM4E | |
| SCHEMBL29217034 | 0.79 | CCR2 (0.50) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL27899832 | 0.79 | CNR2 (0.53) | — | |
| SCHEMBL2218077 | 0.78 | KDM4E (0.49) | MEN1KMT2APTGER4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1634881-B1 | HARMINE DERIVATIVES, INTERMEDIATES USED IN THEIR PREPARATION, PREPARATION PROCESSES AND USE THEREOF | XINJIANG HUASHIDAN PHARMACEUTICAL RES CO LTD (CN) | 2011-07-27 | — | — | EP | claimed |