Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 2/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.41 |
| ▸ | GLS | O94925 | 2/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.38 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20280198 | 0.85 | ADRB2 (0.42) | CXCL8ADRB2ADRB1AOC3GLS | |
| SCHEMBL31287400 | 0.80 | GAA (0.43) | KMT2AMMP2MMP9HIF1A | |
| SCHEMBL11075944 | 0.80 | CXCL8 (0.39) | CXCL8ADRB2ADRB1AOC3NISCH | |
| SCHEMBL27893666 | 0.80 | HTT (0.45) | KMT2AMMP2MMP9 | |
| SCHEMBL13879248 | 0.79 | CASP1 (0.48) | CXCL8ADRB2ADRB1AOC3NISCH | |
| SCHEMBL20536529 | 0.79 | CYSLTR2 (0.46) | CXCL8ADRB2ADRB1GLSCASP1 | |
| SCHEMBL9284882 | 0.78 | ADRB2 (0.44) | ADRB2ADRB1AOC3GLSNISCH | |
| SCHEMBL9232403 | 0.78 | ADRB2 (0.44) | ADRB2ADRB1AOC3GLSNISCH | |
| SCHEMBL17755075 | 0.77 | ADRB2 (0.47) | CXCL8ADRB2ADRB1AOC3NISCH | |
| SCHEMBL6222532 | 0.77 | NISCH (0.50) | ADRB2ADRB1AOC3NISCHSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020141734-A1 | METHOD FOR PREPARING CHIRAL GAMMA-LACTAM COMPOUND AND METAL COMPLEX THEREFOR | 기초과학연구원 | 2020-07-09 | — | — | WO | disclosed |