Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 7/20 | 0.54 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.50 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.49 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | FLT1 | P17948 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201269 | 0.83 | ACP1 (0.55) | ACP1ABCG2TGFBR1ABCB1ABCC1 | |
| SCHEMBL22201268 | 0.81 | TGFBR1 (0.51) | TGFBR1CLK1PIK3CAEGFRFLT1 | |
| SCHEMBL12090776 | 0.78 | ACP1 (0.76) | ACP1ABCG2TGFBR1ABCB1ABCC1 | |
| SCHEMBL17154420 | 0.76 | TGFBR1 (0.57) | TGFBR1EGFRFLT1POLBRAD52 | |
| SCHEMBL22201279 | 0.75 | ABCG2 (0.85) | ACP1ABCG2TGFBR1ABCB1ABCC1 | |
| SCHEMBL8788878 | 0.73 | CLK1 (0.58) | CLK1ROCK2 | |
| SCHEMBL6001853 | 0.72 | ACP1 (0.64) | ACP1ABCG2ABCB1 | |
| SCHEMBL5801453 | 0.72 | ACP1 (0.64) | ACP1ABCG2ABCB1POLB | |
| SCHEMBL13154697 | 0.72 | TGFBR1 (0.71) | ABCG2TGFBR1ROCK2 | |
| SCHEMBL29395013 | 0.72 | TGFBR1 (0.71) | ABCG2TGFBR1ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |