Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 8/20 | 0.85 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | GSK3A | P49840 | 1/20 | 0.65 |
| ▸ | GSK3B | P49841 | 1/20 | 0.65 |
| ▸ | ACP1 | P24666 | 7/20 | 0.59 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.58 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.58 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12090776 | 0.83 | ACP1 (0.76) | ABCG2ALDH1A1POLBGSK3AGSK3B | |
| SCHEMBL22201282 | 0.80 | HPGD (0.64) | ABCG2ALDH1A1POLBLMNAHPGD | |
| SCHEMBL6001853 | 0.79 | ACP1 (0.64) | ABCG2ACP1ABCB1 | |
| SCHEMBL1083761 | 0.79 | HPGD (1.00) | ABCG2ALDH1A1POLBLMNAHPGD | |
| SCHEMBL12090674 | 0.77 | TGFBR1 (0.61) | ABCG2ALDH1A1LMNAHPGDACP1 | |
| SCHEMBL22201369 | 0.77 | LMNA (0.63) | ABCG2ALDH1A1POLBLMNAHPGD | |
| SCHEMBL22201269 | 0.76 | ACP1 (0.55) | ABCG2ALDH1A1POLBACP1ABCB1 | |
| SCHEMBL12090610 | 0.76 | ACP1 (0.60) | ABCG2ACP1ABCB1ABCC1TGFBR1 | |
| SCHEMBL22201261 | 0.75 | ACP1 (0.54) | ABCG2ALDH1A1POLBGSK3AGSK3B | |
| SCHEMBL12090581 | 0.75 | ACP1 (0.67) | ABCG2ACP1ABCB1ABCC1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |