Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 18/20 | 0.54 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.52 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201295 | 0.83 | KDM4E (0.56) | ABCG2 | |
| SCHEMBL22201422 | 0.83 | ABCG2 (0.60) | ABCG2TGFBR1 | |
| SCHEMBL22201431 | 0.83 | PRKD1 (0.54) | ABCG2PRKD1TGFBR1 | |
| SCHEMBL22201614 | 0.82 | TGFBR1 (0.56) | ABCG2PRKD1TGFBR1 | |
| SCHEMBL22201612 | 0.82 | LMNA (0.53) | ABCG2PRKD1TGFBR1 | |
| SCHEMBL22201297 | 0.81 | ABCG2 (0.50) | ABCG2 | |
| SCHEMBL22201280 | 0.81 | ABCG2 (0.50) | ABCG2 | |
| SCHEMBL22201426 | 0.81 | ABCG2 (0.54) | ABCG2 | |
| SCHEMBL22201258 | 0.80 | ABCG2 (0.48) | ABCG2 | |
| SCHEMBL22201674 | 0.78 | HPGD (0.64) | ABCG2PRKD1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |