Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 19/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201559 | 0.87 | HPGD (0.58) | ABCG2LMNAMAPTHPGD | |
| SCHEMBL22201295 | 0.84 | KDM4E (0.56) | ABCG2 | |
| SCHEMBL22201586 | 0.84 | PRKCH (0.47) | ABCG2LMNAMAPTHPGD | |
| SCHEMBL22201432 | 0.83 | LATS1 (0.47) | ABCG2LMNAMAPTHPGD | |
| SCHEMBL22201692 | 0.83 | KDM4E (0.44) | ABCG2LMNAMAPTHPGD | |
| SCHEMBL22201617 | 0.83 | LMNA (0.48) | ABCG2LMNAMAPTHPGD | |
| SCHEMBL22201280 | 0.82 | ABCG2 (0.50) | ABCG2 | |
| SCHEMBL22201297 | 0.82 | ABCG2 (0.50) | ABCG2 | |
| SCHEMBL22201567 | 0.81 | LMNA (0.37) | ABCG2LMNAMAPTHPGD | |
| SCHEMBL22201284 | 0.80 | ABCG2 (0.54) | ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |