Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.64 |
| ▸ | HTR7 | P34969 | 5/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201333 | 0.81 | MAPT (0.58) | PGRTSHRSMN1; SMN2POLB | |
| SCHEMBL8348067 | 0.81 | GAA (0.55) | GAATSHRALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL12963521 | 0.80 | GAA (0.54) | PGRGAATSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL10704403 | 0.78 | ABCB1 (0.60) | GAATSHRALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL12933334 | 0.78 | GAA (0.52) | GAATSHRALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL8347798 | 0.78 | GAA (0.52) | GAATSHRALDH1A1SMN1; SMN2CNR2 | |
| SCHEMBL18028054 | 0.77 | TSHR (0.64) | HTR7TSHRALDH1A1CNR2CNR1 | |
| SCHEMBL22201345 | 0.75 | PGR (0.72) | PGRSMN1; SMN2POLBMAPK8HDAC1 | |
| SCHEMBL7651124 | 0.75 | PGR (0.68) | PGRHTR7ALDH1A1SMN1; SMN2POLB | |
| SCHEMBL13354921 | 0.74 | CNR2 (0.53) | HTR7GAATSHRCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |