Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 19/20 | 0.84 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.70 |
| ▸ | POLB | P06746 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | GSK3A | P49840 | 1/20 | 0.70 |
| ▸ | GSK3B | P49841 | 1/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1083761 | 0.82 | HPGD (1.00) | ABCG2ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL22201422 | 0.82 | ABCG2 (0.60) | ABCG2LMNAHPGD | |
| SCHEMBL4840411 | 0.81 | ABCG2 (0.86) | ABCG2ALDH1A1POLBHPGD | |
| SCHEMBL20299226 | 0.79 | HPGD (0.80) | ABCG2ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL20547707 | 0.79 | HPGD (0.80) | ABCG2ALDH1A1LMNAPOLBHPGD | |
| SCHEMBL22201397 | 0.78 | ABCG2 (0.55) | ABCG2 | |
| SCHEMBL22201270 | 0.78 | MEN1 (0.61) | ABCG2ALDH1A1LMNAHPGD | |
| SCHEMBL22201393 | 0.78 | ABCG2 (0.55) | ABCG2 | |
| SCHEMBL22201285 | 0.78 | ABCG2 (0.55) | ABCG2 | |
| SCHEMBL22201408 | 0.78 | ABCG2 (0.53) | ABCG2ALDH1A1LMNAPOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |