Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 17/20 | 0.55 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22201285 | 0.91 | ABCG2 (0.55) | ABCG2 | |
| SCHEMBL22201397 | 0.85 | ABCG2 (0.55) | ABCG2 | |
| SCHEMBL22201251 | 0.83 | MKNK1 (0.47) | ABCG2MKNK1ROCK2TGFBR1 | |
| SCHEMBL22201396 | 0.82 | TGFBR1 (0.53) | ABCG2MKNK1ROCK2TGFBR1 | |
| SCHEMBL22201422 | 0.82 | ABCG2 (0.60) | ABCG2TGFBR1 | |
| SCHEMBL22201259 | 0.81 | ABCG2 (0.51) | ABCG2 | |
| SCHEMBL3041415 | 0.80 | TGFBR1 (0.47) | ABCG2MKNK1ROCK2TGFBR1 | |
| SCHEMBL6694913 | 0.79 | LATS1 (0.57) | ABCG2ROCK2TGFBR1 | |
| SCHEMBL14320793 | 0.79 | CLK1 (0.49) | MKNK1ROCK2TGFBR1 | |
| SCHEMBL22201398 | 0.78 | ABCG2 (0.84) | ABCG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020142748-A1 | METHODS AND MATERIALS FOR INCREASING TRANSCRIPTION FACTOR EB POLYPEPTIDE LEVELS | UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2020-07-09 | — | — | WO | disclosed |